Results 131 to 140 of about 78,497,869 (306)

University Hospitals General Staff Meeting, April 6, 1931

open access: yes, 1931
University of Minnesota. University of Minnesota Hospitals. (1931). University Hospitals General Staff Meeting, April 6, 1931.
University of Minnesota. University of Minnesota Hospitals
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

University Hospitals Staff Meeting Bulletin, February 8, 1934

open access: yes, 1934
University of Minnesota. University of Minnesota Hospitals. (1934). University Hospitals Staff Meeting Bulletin, February 8, 1934.
University of Minnesota. University of Minnesota Hospitals
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

University Hospitals Staff Meeting Bulletin, April 5, 1934

open access: yes, 1934
University of Minnesota. University of Minnesota Hospitals. (1934). University Hospitals Staff Meeting Bulletin, April 5, 1934.
University of Minnesota. University of Minnesota Hospitals
core  

Assessing performance of Guilan university hospitals (2012)

open access: yesThe Journal of Qazvin University of Medical Sciences, 2016
Background: Performance assessment could provide information to control and monitor of the current status and activities in hospitals. Objective: To assess the performance of hospitals affiliated with Guilan University of Medical Sciences in 2012 ...
M. Alijanzadeh   +3 more
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

University Hospitals Staff Meeting Bulletin, February 7, 1935

open access: yes, 1935
University of Minnesota. University of Minnesota Hospitals. (1935). University Hospitals Staff Meeting Bulletin, February 7, 1935.
University of Minnesota. University of Minnesota Hospitals
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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