Results 121 to 130 of about 78,497,869 (306)
University Hospitals Staff Meeting Bulletin, March 1, 1934
, 1934 University of Minnesota. University of Minnesota Hospitals. (1934). University Hospitals Staff Meeting Bulletin, March 1, 1934.
University of Minnesota. University of Minnesota Hospitals
core
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
University Hospitals General Staff Meeting, March 17, 1932
, 1932 University of Minnesota. University of Minnesota Hospitals. (1932). University Hospitals General Staff Meeting, March 17, 1932.
University of Minnesota. University of Minnesota Hospitals
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
University Hospitals General Staff Meeting, October 6, 1932
, 1932 University of Minnesota. University of Minnesota Hospitals. (1932). University Hospitals General Staff Meeting, October 6, 1932.
University of Minnesota. University of Minnesota Hospitals
core
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
University Hospitals General Staff Meeting, December 15, 1932
, 1932 University of Minnesota. University of Minnesota Hospitals. (1932). University Hospitals General Staff Meeting, December 15, 1932.
University of Minnesota. University of Minnesota Hospitals
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
University Hospitals Staff Meeting Bulletin, November 7, 1935
, 1935 University of Minnesota. University of Minnesota Hospitals. (1935). University Hospitals Staff Meeting Bulletin, November 7, 1935.
University of Minnesota. University of Minnesota Hospitals
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source