Results 21 to 30 of about 2,341,112 (317)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Comparative Study of Organizational Culture in Public and University Libraries and its Relationship with the Users’ Satisfaction [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2012
Purpose: The purpose of the present article is comparatively study of the organizational culture in Tehran city public and university libraries and its relationship with the user’s satisfaction. Method: This research is an applied type research conducted
Mohammad Hassanzadeh, Elmira Karimi
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Marketing Mix in the Websites Operated by Central Libraries in Iranian Universities [PDF]

open access: yesتحقیقات کتابداری و اطلاع‌رسانی دانشگاهی, 2011
Objective: The present investigation intends to identify the marketing techniques employed within the websites set up by central libraries of Iranian Universities. Methodology: An analytical survey was used.
F Nooshinfar, S Ziyaie
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The University Libraries Methodic Association: partnership and collaboration

open access: yesБиблиосфера, 2016
The article describes organization of the University Libraries Methodic Association (MA) activity in Krasnoyarsk, the importance of professional units and their interaction with public organizations and associations. The article highlights sections work,
V. P. Kazantseva, R. A. Baryshev
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Budgeting in University Libraries

open access: yesSerials: The Journal for the Serials Community, 1991
The budgeting process in university libraries is assessed. Following consideration of the political context, approaches to costing of staff activities are discussed and other expenditure which has to be given priority either in compiling estimates or in setting a budget are identified.
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Analysis of Strategic Planning Content and Development Trends of American University Libraries [PDF]

open access: yesNongye tushu qingbao xuebao
[Purpose/Significance] American university libraries have accumulated rich experience in strategic planning with their advanced concepts and practices. This article analyzes the content and development trends of strategic planning in American university ...
Xiao SHI
doaj   +1 more source

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