Results 31 to 40 of about 78,445,766 (260)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Spiritual Intelligence and Mental Health of Librarians of Academic Libraries [PDF]
بازیابی دانش و نظامهای معنایی, 2017 This study aims to evaluate the relationship between spiritual intelligence and mental health among librarians working in academic libraries. This study is a descriptive-correlational study. The study population consisted of 210 librarians working in the
Oranus Tajedini +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Noteworthy: News Briefs from PA Libraries
Pennsylvania Libraries: Research & Practice, 2014 Accomplishments, experiences, events, and news about Pennsylvania librarians and libraries. In this issue: Chatham University Appointments and Professional Development Clarion University Libraries Appoint Two New Library Faculty Duquesne University ...
Linda Neyer, Larissa Gordon
doaj +1 more source
Journal of Librarianship and Scholarly Communication, 2023 Introduction: This mixed-method study analyzes the self-archiving behaviors and underlying motivations of researchers at an institution very recently recategorized by the Carnegie Classification system from “Doctoral– High Research Activity (R2)” to ...
Jack Maness +3 more
doaj +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Rethinking Representation: Indigenous Peoples and Contexts at the University of Alberta Libraries
The International Journal of Information, Diversity, & Inclusion, 2018 Appropriate subject access and descriptive practices within library and information science are social justice issues. Standards that are well established and commonly used in academic libraries in Canada and elsewhere, including Library of Congress ...
Sharon Farnel +6 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The Ohio State University Libraries Faculty Meeting Minutes, March 2, 2021
, 2021 The University Archives has determined that this item is of continuing value to OSU's ...
Ohio State University. Libraries
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Inclusion of Social Media and Digital Infrastructures in Marketing Library Products and Services in Central Libraries of Multi-Disciplinary Universities in Kerala [PDF]
International Journal of Information Science and ManagementSocial networking tools are the inevitable essence of life. The flexible structure of social networks paves the way for communication and collaboration between users and librarians. So here, the paper constitutes a study of the central libraries of Four
Aswathy Ajayan, Thanuskodi S
doaj +1 more source