Results 31 to 40 of about 1,699,899 (309)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Portals and university libraries [PDF]

, 2011
Section 2: Chapter ...
MacColl, John
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Boston University Libraries 2016 Graduate Survey Instrument [PDF]

, 2016
In the spring of 2016, the Boston University libraries surveyed BU faculty, graduate students, and undergraduate students to determine their use of and satisfaction with library services and resources. This document shows the survey instrument emailed to
Boston University Libraries Assessment Committee
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Analysis of Strategic Planning Content and Development Trends of American University Libraries [PDF]

Nongye tushu qingbao xuebao
[Purpose/Significance] American university libraries have accumulated rich experience in strategic planning with their advanced concepts and practices. This article analyzes the content and development trends of strategic planning in American university ...
Xiao SHI
doaj   +1 more source

Scholarship, Libraries, and Open Access Archiving Initiative [PDF]

, 2009
The resolution passed by the BU University Council approving an initiative to establish an archive of the research and scholarship produced by the faculty of the ...
Boston University, Faculty Council, Committee on Research Activities, Libraries, and Support services, Boston University, University Council, Committee on Scholarly Activies and Libraries   +1 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

One Size Does Not Fit All: Self-Archiving Personas Based On Federally Funded Researchers at a Mid-Sized Private Institution

Journal of Librarianship and Scholarly Communication, 2023
Introduction: This mixed-method study analyzes the self-archiving behaviors and underlying motivations of researchers at an institution very recently recategorized by the Carnegie Classification system from “Doctoral– High Research Activity (R2)” to ...
Jack Maness, Jenelys Cox, Jenny Bowers, Meg M Eastwood   +3 more
doaj   +2 more sources

New Trends in Digital University Libraries [PDF]

, 2003
The nature of the changes that university libraries face in the digital age is addressed in the document. Work and training schemes for all those involved in the process of electronic publishing within universities are proposed. The role of libraries and
Peter, Schirmbacher
core