Results 41 to 50 of about 486,392 (266)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Research on Tabriz University of Medical Sciences Libraries Staff, Collection, Space and Budget Comparison with Iranian University Libraries Standards

مدیریت اطلاعات سلامت, 2010
Introduction: Academic libraries are famous to be the hearts of universities, with the ever increasing importance of the evaluation of information technologies in academic centers, and libraries need to evaluate their status to accord with these ...
Kamal Ebrahimi, Shafi Habibi, Gholamhossein Tasbihi   +2 more
doaj  

Inclusion of Social Media and Digital Infrastructures in Marketing Library Products and Services in Central Libraries of Multi-Disciplinary Universities in Kerala [PDF]

International Journal of Information Science and Management
Social networking tools are the inevitable essence of life. The flexible structure of social networks paves the way for communication and collaboration between users and librarians.  So here, the paper constitutes a study of the central libraries of Four
Aswathy Ajayan, Thanuskodi S
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A Comparative Study of Social Capital in Academic Libraries; A Comparison of Tehran University Libraries With Sharif University Libraries [PDF]

تحقیقات کتابداری و اطلاع‌رسانی دانشگاهی, 2015
Objectives: This research is a comparative study of the level of social capital in Tehran University and Sharif University of Technology libraries.Method: The research method is composed of survey and comparative study.
Nahid Jafari, Maryam Nakhoda, Gholam Reza Fadaei   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Information technologies in Mansoura University libraries: a field study. 1

Cybrarians Journal, 2011
A comprehensive study on the application of information technology in the libraries of Mansoura University. The study begins with a methodological introduction, then begins to address the aspects of information technology in the university libraries,
Ashraf Mansour
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Information technologies in Mansoura University libraries: a field study. 2

Cybrarians Journal, 2011
A comprehensive study on the application of information technology in the libraries of Mansoura University. The study begins with a methodological introduction, then begins to address the aspects of information technology in the university libraries ...
Ashraf Mansour
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source