Results 61 to 70 of about 2,341,112 (317)

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

The marketing of university libraries, with special reference to South African university libraries

open access: yes, 1990
Bibliography: leaves 251-262.The investigation was undertaken to establish, in the first place, whether it is correct to assume that university library managers in South Africa do understand the main tenets of marketing.
Syphus, Matthew
core  

The Ohio State University Libraries Faculty Meeting Minutes, February 11, 2020

open access: yes, 2020
The University Archives has determined that this item is of continuing value to OSU's ...
Ohio State University. Libraries
core  

The Ohio State University Libraries Faculty Meeting Minutes, April 25, 2023

open access: yes, 2023
The University Archives has determined that this item is of continuing value to OSU's ...
Ohio State University. Libraries
core  

People-First Promotion: Rallying Library Workers during COVID-19 and Beyond [PDF]

open access: yesMarketing Libraries Journal, 2021
COVID-19 forced workers around the world to face the realities of closed buildings, precarious employment situations, and challenges to their well-being.
Kelly, Katy   +3 more
doaj  

University Libraries and University Research

open access: yesCollege & Research Libraries, 1972
Made available in DSpace on 2013-01-30T21:49:22Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) crl_33_06_447_opt.pdf: 1172552 bytes, checksum: bc465ff83410160bda826ef62cea71ab (MD5) Previous issue date: 1972-11 ; published or submitted for ...
Redmond, Donald A.   +2 more
openaire   +2 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

2016: University Libraries Annual Report 2015-2016

open access: yes, 2016
Goals 1-7 -- Faculty research -- University Libraries by the numbers
University Libraries
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

LibQual+ 2007 Survey: University of North Texas Libraries

open access: yes, 2007
This report contains information from the 2007 administration of the LibQUAL+™ protocol at University of North Texas Libraries. Based on the SERVQUAL model, the purpose of the LibQUAL+® survey is to provide libraries with an objective tool to measure ...
Association of Research Libraries
core  

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