Results 61 to 70 of about 78,445,766 (260)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

LibQual+ 2007 Survey: University of North Texas Libraries

, 2007
This report contains information from the 2007 administration of the LibQUAL+™ protocol at University of North Texas Libraries. Based on the SERVQUAL model, the purpose of the LibQUAL+® survey is to provide libraries with an objective tool to measure ...
Association of Research Libraries
core  

Strategi Pengelolaan Unit Penunjang Universitas Perpustakaan Universitas Gadjah Mada 'Yogyakarta (Strategy of Management of Gadjah Mada University Libraries Yogyakarta)

Berkala Ilmu Perpustakaan dan Informasi, 2015
Gadjah Mada University Libraries are expected to provide a better fast, easy and efficient service. In the past few years, there were some changes at the Gadjah Mada University Libraries; moreover Gadjah Mada University is stated to be a research ...
Wahyu Supriyanto, Sunyoto Usman, I Gusti Ngurah Putra   +2 more
doaj   +1 more source

People-First Promotion: Rallying Library Workers during COVID-19 and Beyond [PDF]

Marketing Libraries Journal, 2021
COVID-19 forced workers around the world to face the realities of closed buildings, precarious employment situations, and challenges to their well-being.
Kelly, Katy, Beis, Christina A., Zlotnik, Ann, Schlangen, Maureen E.   +3 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

LibQual+ 2009 Survey: University of North Texas Libraries

, 2009
This report contains information from the 2009 administration of the LibQUAL+™ protocol at University of North Texas Libraries. Based on the SERVQUAL model, the purpose of the LibQUAL+® survey is to provide libraries with an objective tool to measure ...
Association of Research Libraries
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

LibQual+ 2011 Survey: University of North Texas Libraries

, 2011
This report contains information from the 2011 administration of the LibQUAL+™ protocol at University of North Texas Libraries. Based on the SERVQUAL model, the purpose of the LibQUAL+® survey is to provide libraries with an objective tool to measure ...
Association of Research Libraries
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Using 4P Marketing Model in Academic Libraries: An Experience

International Journal of Information Science and Management, 2013
The present study mainly aims to demonstrate the weaknesses and strengths of using marketing principles in academic libraries and finally presenting some important suggestions in order to improve their marketing.
Mehdi Alipour Hafezi, Hassan Ashrafi Rizi, Zahra Kazempour, Mahri Shahbazi   +3 more
doaj