Results 71 to 80 of about 486,392 (266)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Naim Frashëri - Founder and professor of Albanian literature for children

open access: yesAcademicus International Scientific Journal, 2012
Between the obligation of carrying out their mission to ensure the quality development of higher education and the right to function as important centers where knowledge is taken, developed and transmitted, this paper will examine the technological ...
Rudina Alimerko
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Building Resilience and Safe Guiding Strategies for University Libraries in Disaster-Prone Areas

open access: yesPakistan Journal of Information Management & Libraries
University libraries in disaster-prone areas are increasingly at risk from natural and man-made disasters, such as earthquakes, floods, fires, and technology meltdowns, which can disrupt library services and potentially lead to the loss of valuable ...
Saima Hanif, Muhammad Awais
doaj  

Development of Higher Education in Albania: The Case of the Public University Libraries in Efforts to Build Digital and Electronic Services for the Academic Community

open access: yesAcademicus International Scientific Journal, 2013
Between the obligation of carrying out their mission to ensure the quality development of higher education and the right to function as important centers where knowledge is taken, developed and transmitted, this paper will examine the technological ...
Erena Haska
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Economic Relations between Italy and Albania 1993 – 2000

open access: yesAcademicus International Scientific Journal, 2012
Between the obligation of carrying out their mission to ensure the quality development of higher education and the right to function as important centers where knowledge is taken, developed and transmitted, this paper will examine the technological ...
Juliana Marko
doaj   +1 more source

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