Results 101 to 110 of about 5,914,724 (274)
BackgroundNovel HIV pre-exposure prophylaxis (PrEP) methods including a potential future HIV vaccine, will increase prevention options for adolescent girls and young women (AGYW) at high risk of HIV infection in Eastern and Southern Africa, yet data on ...
Yunia Mayanja +12 more
doaj +1 more source
Black and white image of a man identified as Joseph Marion Murphy. Non-mounted image.Master file: image/tiff; 213,214 KB: Computer Hardware: Intel Pentium (R) 4 3.20 GHz/ 1.99 GB RAM manufactured by Dell; Operating system: Windows XP 2002; Creation ...
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Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Using dictator game, we evaluated participants (N = 80 students) social value orientations and found that prosocial orientation was shared by the majority of the participants.
Loredana Ivan
doaj
Discerning the impact of ctDNA detection on patient decision-making in early-stage breast cancer
The impact of knowledge of circulating tumor DNA (ctDNA) status on patient decisions in high-risk triple-negative breast cancer (TNBC) weighing benefit and toxicity is unknown.
Tarah J. Ballinger +4 more
doaj +1 more source
Sepia image of 12 unidentified cowboys, each sitting on their horses. Background; a large heard of cattle. Verso; Written in Blue ink; ""At Harry martin's Ranch?"" Image mounted on black embossed matte board.Master file: image/tiff; 131,947 KB: Computer ...
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The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Black and white image of a few buildings on the grounds of St. Mary's Academy, Silver City. Eight unidentified boys play in front of the building to the right. One unidentified nun stands watching the boys.
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PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Sepia image of a man and a young boy astride a horse, both unidentified, posed in front of a small ranch house. Verso; Written in blue ink; ""Harry Martin ranch."" Non-mounted image.Master file: image/tiff; 144,809 KB: Computer Hardware: Intel Pentium (R)
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