Results 121 to 130 of about 6,759,956 (334)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Understanding HIV service preferences of South African women 30–49 years old missing from or linked to care: An exploratory study of Gauteng and Limpopo provinces

Women's Health
Background: The HIV epidemic in sub-Saharan Africa has a disproportionate gender impact, with women bearing the brunt of the epidemic. South Africa carries the largest share of the global HIV burden, with similar trends seen for women due to unequal ...
Aneesa Moolla, Michael Galvin, Constance Mongwenyana, Jacqui Miot, William Magolego, Patricia Leshabana, Nkosinathi Ngcobo, Nalini Naidoo, Lezanie Coetzee   +8 more
doaj   +1 more source

The role of previous foreign language knowledge when translating from Italian as an unknown language into L2 English or L3 Spanish or French

Moderna Språk, 2019
The aim of the present study is to examine and describe Swedish upper secondary students’ use of their background languages while translating a text from Italian, a language unknown to them, into either their L2 English or their L3 French or Spanish. The
Linda Smidfelt, Joost van de Weijer
doaj   +1 more source

Associations between social risk factors and surgical site infections after colectomy and abdominal hysterectomy [PDF]

, 2019
Importance: Surgical site infection (SSI) is an important patient safety outcome. Although social risk factors have been linked to many adverse health outcomes, it is unknown whether such factors are associated with higher rates of SSI.
Barker, Abigail, Joynt Maddox, Karen E, Luke, Alina A, Olsen, Margaret A, Peacock, Kate, Qi, Andrew C   +5 more
core   +1 more source

Morphological and clinical findings in Sri Lankan patients with chronic kidney disease of unknown cause (CKDu): Similarities and differences with Mesoamerican Nephropathy

PLoS ONE, 2018
In Sri Lanka, an endemic of chronic kidney disease of unknown origin (CKDu) is affecting rural communities. The endemic has similarities with Mesoamerican Nephropathy (MeN) in Central America, however it has not yet been clarified if the endemics are ...
Julia Wijkström, C. Jayasumana, R. Dassanayake, Nalin Priyawardane, Nimali Godakanda, S. Siribaddana, Anneli Ring, K. Hultenby, M. Söderberg, C. Elinder, A. Wernerson   +10 more
semanticscholar   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Testing the social competition hypothesis of depression using a simple economic game

BJPsych Open, 2016
BackgroundPrice's social competition hypothesis interprets the depressive state as an unconscious, involuntary losing strategy, which enables individuals to yield and accept defeat in competitive situations.AimsWe investigated whether patients who suffer
Aleksandra Kupferberg, Oliver M. Hager, Urs Fischbacher, Laura S. Brändle, Melanie Haynes, Gregor Hasler   +5 more
doaj   +1 more source

Is There Selection Bias in Laboratory Experiments? The Case of Social and Risk Preferences [PDF]

Laboratory experiments are frequently used to examine the nature of individual preferences and inform economic theory. However, it is unknown whether the preferences of volunteer participants are representative of the population from which the ...
Cleave, Blair L., Nikiforakis, Nikos, Slonim, Robert   +2 more
core  

First-time mothers' expectations of the unknown territory of childbirth: Uncertainties, coping strategies and 'going with the flow'.

Midwifery, 2018
OBJECTIVE To explore first-time mothers' expectations of labour and birth, coping strategies they adopt during pregnancy towards childbirth and coping strategies they expect to use during labour and birth.
S. Borrelli, D. Walsh, H. Spiby
semanticscholar   +1 more source