Results 131 to 140 of about 1,288,650 (300)

Study and design of amino acid-based radical enzymes using unnatural amino acids. [PDF]

RSC Chem Biol, 2023
Yuan F, Su B, Yu Y, Wang J.
europepmc   +1 more source

Postprandial Levels of Branch Chained and Aromatic Amino Acids Associate with Fasting Glycaemia [Elektronisk resurs]

, 2016
High fasting plasma concentrations of isoleucine, phenylalanine, and tyrosine have been associated with increased risk of hyperglycaemia and incidence of type 2 diabetes. Whether these associations are diet or metabolism driven is unknown.
Nilsson, Jeanette, Fernandez, Celine,, Ericson, Ulrika,, Magnusson, Martin,, Melander, Olle,, Lund University., Almgren, Peter,, Ottosson, Filip,   +7 more
core   +1 more source

Radical‐Mediated In Situ Fluorescence Dye Deposition: A Simple Interfacial Signal Amplification Reaction for Ultrasensitive Immunoassay on Barcode Beads

Advanced Science, EarlyView.
A radical‐mediated in situ fluorescence dye deposition (RIFD) reaction containing merely three elements of beads, dyes, and radicals is discovered for the first time, and its underlying mechanism is elucidated. This simple RIFD enables the interfacial and ultrafast deposition of free dyes onto barcode beads, serving as a powerful signal amplification ...
Jiayu Zhang, Yao Wang, Xinyi Huang, Haiyu Wu, Qiuning Lin, Hongchen Gu, Li Jiang, Linyong Zhu, Hong Xu   +8 more
wiley   +1 more source

Computational investigation of the effect of BODIPY labelling on peptide-membrane interaction

Scientific Reports
Optical monitoring of peptide binding to live cells is hampered by the abundance of naturally occurring fluorophores such as tryptophan. Unnatural amino acids incorporating synthetic fluorophores such as BODIPY overcome these optical limitations.
Dominique de Jong-Hoogland, Jacob Ulmschneider, Martin Ulmschneider   +2 more
doaj   +1 more source

Reprogramming natural proteins using unnatural amino acids. [PDF]

RSC Adv, 2021
Adhikari A, Bhattarai BR, Aryal A, Thapa N, Kc P, Adhikari A, Maharjan S, Chanda PB, Regmi BP, Parajuli N.   +9 more
europepmc   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Synthesis of Enantiopure Unnatural Amino Acids by Metallaphotoredox Catalysis. [PDF]

Org Process Res Dev, 2021
Faraggi TM, Rouget-Virbel C, Rincón JA, Barberis M, Mateos C, García-Cerrada S, Agejas J, de Frutos O, MacMillan DWC.   +8 more
europepmc   +1 more source

Blood amino acids concentration during insulin induced hypoglycemia in rats: the role of alanine and glutamine in glucose recovery

, 2015
Our purpose was to determine the blood amino acid concentration during insulin induced hypoglycemia (IIH) and examine if the administration of alanine or glutamine could help glycemia recovery in fasted rats.
Gazola, VAFG, Hartmann, EM, Manso, FC, Barrena, HC, Carneiro, EM, Bazotte, RB, Garcia, RF, Berti, J, Toyama, MH, Boschero, AC   +9 more
core   +1 more source

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

Stereoselective synthesis towards unnatural proline based amino acids

ARKIVOC, 2016
Sifiso S.Makhathini, Sukant K. Das, Thishana Singh, Per I. Arvidsson, Hendrik G. Kruger, Hendra Gunosewoyo, Thavendran Govender, Tricia Naicker   +7 more
doaj   +1 more source