Results 261 to 270 of about 1,288,650 (300)

New Developments in the Synthesis of Natural and Unnatural Amino Acids

Annals of the New York Academy of Sciences, 1992
SUMMARYAmino acids play an important role in biochemistry and chemistry. They are the building blocks of proteins and play an essential role in the regulation of the metabolism of living organisms.In general, it can be stated that microbial processes (fermentation) are the industrial production methods of choice for large‐scale production of naturally ...
Kamphuis, J., Meijer, E.M., Boesten, W.H.J., Sonke, T., Tweel, van den, W.J.J., Schoemaker, H.E.   +5 more
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Unnatural Amino Acids for Biological Spectroscopy and Microscopy

Chemical Reviews
Due to advances in methods for site-specific incorporation of unnatural amino acids (UAAs) into proteins, a large number of UAAs with tailored chemical and/or physical properties have been developed and used in a wide array of biological applications. In particular, UAAs with specific spectroscopic characteristics can be used as external reporters to ...
Ran-ran Feng, Manxi Wang, Wenkai Zhang, Feng Gai   +3 more
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Protein and Cellular Engineering with Unnatural Amino Acids

Biotechnology Progress, 2007
Abstract Proteins are the central functional constituents in all living organisms ranging from viruses, bacteria, yeast, and plants to mammals. All of these biopolymers that are formed by natural biosynthetic pathways are composed of a genetically determined sequence of the 20 so‐called natural amino acids.
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Unnatural Protein Engineering: Producing Proteins with Unnatural Amino Acids

Medicinal Chemistry Reviews - Online, 2005
Less than a decade ago, the ability to generate proteins with unnatural modifications was a Herculean task available only to specialty labs. Recent advances make it possible to generate reasonable quantities of protein with un- natural amino acids both in vitro and in vivo .
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ChemInform Abstract: Unnatural Amino Acids

ChemInform, 2008
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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A Radical Approach to Making Unnatural Amino Acids: Conversion of C−S Bonds in Cysteine Derivatives into C−C Bonds

Angewandte Chemie - International Edition, 2021
Xia Zhang, Dawen Niu, Yingwei Wang
exaly  

Methods for the synthesis of unnatural amino acids.

Current opinion in drug discovery & development, 2002
A wide variety of methods have been used to prepare unnatural amino acids. This review covers methods reported between 2000 and the early part of 2001. Some of the approaches discussed are applications of established methods, but emphasis has been given to new approaches that could be generally applicable to large-scale syntheses, including catalytic ...
D J, Ager, I G, Fotheringham
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Unnatural Amino Acids

2007
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Unnatural Amino Acid Mutagenesis of Fluorescent Proteins

Angewandte Chemie, 2012
Feng, Wang, Wei, Niu, Jiantao, Guo, Peter G, Schultz   +3 more
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Radical-Mediated C−H Alkylation of Glycine Derivatives: A Straightforward Strategy for Diverse α-Unnatural Amino Acids

European Journal of Organic Chemistry, 2022
Jaehoon Sim
exaly