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Applications of Unnatural Amino Acids in Protease Probes
Chemistry – An Asian Journal, 2019AbstractSince proteases are involved in a wide range of physiological and disease states, the development of novel tools for imaging proteolytic enzyme activity is attracting increasing interest from scientists. Peptide substrates containing proteinogenic amino acids are often the first line of defining enzyme specificity.
Izabela Maluch +2 more
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Multistep Enzyme Catalyzed Reactions for Unnatural Amino Acids
2011The use of unnatural amino acids, particularly synthetic α-amino acids, for modern drug discovery research requires the availability of enantiomerically pure isomers. Starting from a racemate, one single enantiomer can be obtained using a deracemization process.
D'ARRIGO, PAOLA, TESSARO, DAVIDE
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Protein and Cellular Engineering with Unnatural Amino Acids
Biotechnology Progress, 2007Abstract Proteins are the central functional constituents in all living organisms ranging from viruses, bacteria, yeast, and plants to mammals. All of these biopolymers that are formed by natural biosynthetic pathways are composed of a genetically determined sequence of the 20 so‐called natural amino acids.
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Unnatural α-amino acid synthesis
Nature Synthesis, 2023Tuan Anh Trinh, Jennifer M. Schomaker
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Unnatural Amino Acids for Biological Spectroscopy and Microscopy
Chemical ReviewsDue to advances in methods for site-specific incorporation of unnatural amino acids (UAAs) into proteins, a large number of UAAs with tailored chemical and/or physical properties have been developed and used in a wide array of biological applications. In particular, UAAs with specific spectroscopic characteristics can be used as external reporters to ...
Ran-ran Feng +3 more
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Unnatural Amino Acid Mutagenesis of Fluorescent Proteins
Angewandte Chemie, 2012Feng, Wang +3 more
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