Results 21 to 30 of about 246,994 (340)

Sequence analysis and genomic organization of Aphid lethal paralysis virus: a new member of the family Dicistroviridae [PDF]

, 2002
The complete nucleotide sequence of the genomic RNA of an aphid-infecting virus, Aphid lethal paralysis virus (ALPV), has been determined. The genome is 9812 nt in length and contains two long open reading frames (ORFs), which are separated by an ...
Clerivet, A., Dullemans, A.M., Heuvel, J.F.J.M., van den, Munster, M., van, Verbeek, M., Wilk, F., van der   +5 more
core   +2 more sources

Evolutionary and Functional Diversity of the 5′ Untranslated Region of Enterovirus D68: Increased Activity of the Internal Ribosome Entry Site of Viral Strains during the 2010s

Viruses, 2019
The 5′ untranslated region (UTR) of the RNA genomes of enteroviruses possesses an internal ribosome entry site (IRES) that directs translation of the mRNA by binding to ribosomes.
Yuki Furuse, Natthawan Chaimongkol, Michiko Okamoto, Hitoshi Oshitani   +3 more
doaj   +1 more source

Evidence for a posttranscriptional effect of retinoic acid on connexin43 gene expression via the 3′-untranslated region [PDF]

, 1997
All-trans retinoic acid (10−7 M) induces cell–cell communication and the expression of the gap junction protein connexin43 in mouse F9 teratocarcinoma cells.
Clairmont, Annette, Sies, Helmut
core   +1 more source

In vivo detection of lamellocytes in Drosophila melanogaster. [PDF]

, 2009
Drosophila has recently become a powerful model organism for studies of innate immunity. The cellular elements of innate immunity in Drosophila, the hemocytes, have been characterized by morphological criteria, molecular markers, and cell-type-specific ...
Brand, Braun, Carton, Evans, Evans, Goto, Hartenstein, Hoffmann, Hultmark, Konrad, Kurucz, Kurucz, Kurucz, Lanot, Metaxakis, Márkus, Márkus, Zettervall   +17 more
core   +1 more source

Effects of Combinations of Untranslated-Region Sequences on Translation of mRNA [PDF]

Biomolecules, 2023
mRNA-based therapeutics have been found to be a promising treatment strategy in immunotherapy, gene therapy, and cancer treatments. Effectiveness of mRNA therapeutics depends on the level and duration of a desired protein’s expression, which is determined by various cis- and trans-regulatory elements of the mRNA.
Kirshina A, Vasileva O, Kunyk D, Seregina K, Muslimov A, Ivanov R, Reshetnikov V.   +6 more
europepmc   +4 more sources

Selective translation of the measles virus nucleocapsid mRNA by La protein

Frontiers in Microbiology, 2011
Measles, caused by measles virus (MeV) infection, is the leading cause of death in children because of secondary infections attributable to MeV-induced immune suppression.
Yoshihisa eInoue, Hiroki eSato, Kentaro eFujita, Kyoko eTsukiyama-Kohara, Misako eYoneda, Chieko eKai   +5 more
doaj   +1 more source

Preferential regulation of stably expressed genes in the human genome suggests a widespread expression buffering role of microRNAs [PDF]

, 2012
In this study, we comprehensively explored the stably expressed genes (SE genes) and fluctuant genes (FL genes) in the human genome by a meta-analysis of large scale microarray data. We found that these genes have distinct function distributions.
A Krek, A Stark, B John, BP Lewis, C Cheng, CI Wu, CM Denby, D Maret, Dong Dong, DP Bartel, E Hornstein, E Wienholds, F Megiorni, G Stefani, H Dweep, J Krutzfeldt, J Li, J Tsang, KA O'Donnell, KJ Peterson, L He, LF Sempere, Li Wang, M Ashburner, M James C Crabbe, M Kertesz, M Lagos-Quintana, M Selbach, Manu, N Rajewsky, NJ Martinez, P Hao, P Sood, Q Cui, Q Cui, R Zhang, X Li, X Li, X Wu, X Wu, X Xie, X Yuan, Y Zeng, Yang Zhong, Z Yu, Zhaolei Zhang, Zhen Yang   +46 more
core   +1 more source

Influence of untranslated regions on retroviral mRNA transfer and expression [PDF]

BMC Biotechnology, 2013
Abstract Background Deliberate cellular reprogramming is becoming a realistic objective in the clinic. While the origin of the target cells is critical, delivery of bioactive molecules to trigger a shift in cell-fate remains the major hurdle. To date, several strategies based either on non-integrative vectors, protein
Anne Prel, Anne Prel, Jean-Christophe Pages, Luc Sensebé   +3 more
openaire   +3 more sources

XIAP 3′-untranslated region serves as a competitor for HMGA2 by arresting endogenous let-7a-5p in human hepatocellular carcinoma

Tumor Biology, 2017
X-linked inhibitor of apoptosis protein functions as an intrinsic regulator of apoptosis by inhibition of caspase activity and possesses a pivotal role in human cancer development and progression.
Wen-Yong Wu, Si-Qi Tao, Xiao-Nan Wang, Peter E Lobie, Zheng-Sheng Wu   +4 more
doaj   +1 more source

Generation of a GFP Reporter Akabane Virus with Enhanced Fluorescence Intensity by Modification of Artificial Ambisense S Genome

Viruses, 2019
We previously generated a recombinant reporter Akabane virus expressing enhanced green fluorescence protein (eGFP-AKAV), with an artificial S genome encoding eGFP in the ambisense RNA.
Akiko Takenaka-Uema, Shin Murakami, Nanako Ushio, Tomoya Kobayashi-Kitamura, Masashi Uema, Kazuyuki Uchida, Taisuke Horimoto   +6 more
doaj   +1 more source