Results 31 to 40 of about 246,994 (340)

Is there a classical nonsense-mediated decay pathway in trypanosomes? [PDF]

PLoS ONE, 2011
In many eukaryotes, messenger RNAs with premature termination codons are destroyed by a process called "nonsense-mediated decay", which requires the RNA helicase Upf1 and also, usually, an interacting factor, Upf2.
Praveen Delhi, Rafael Queiroz, Diana Inchaustegui, Mark Carrington, Christine Clayton   +4 more
doaj   +1 more source

The Human Pregnancy-Specific Glycoprotein Genes are Tightly Linked on the Long Arm of Chromosome 19 and are Coordinately Expressed [PDF]

, 1990
The pregnancy-specific glycoprotein (PSG) genes encode a group of proteins which are found in large amounts in placenta and maternal serum. In situ hybridization analyses of metaphase chromosomes reveal that all the human pregnancy-specific glycoprotein (
Barnett, Barnett, Barnett, Benton, Bohn, Chan, Chomczynski, Feinberg, Fiddes, Grunert, Hefta, Hinoda, Jean, Kamarck, Khan, Khan, Kolbinger, Lathe, Lin, Maniatis, Neumaier, Niemann, Oikawa, Oikawa, Oikawa, Paxton, Perry, Rooney, Rudert, Sanger, Streydio, Takami, Tatarinov, Thompson, Thompson, Thompson, Watanabe, Watanabe, Willcocks, Zimmermann, Zimmermann   +40 more
core   +1 more source

Evolution of the influenza A virus untranslated regions

Infection, Genetics and Evolution, 2011
In case of the influenza virus, untranslated regions are considered to possess plural functions. The specific packaging model suggests that each of eight segments contains a unique "packaging signal", situated within the untranslated region and coding regions at the 5' and 3' ends of the genomic RNA. In addition to packaging signal, UTRs play key roles
Hitoshi Oshitani, Yuki Furuse
openaire   +2 more sources

Single nucleotide polymorphisms in the CDH18 gene affect growth traits in Hu sheep

Animal Research and One Health, EarlyView., 2023
Abstract Growth traits are critical economic traits in sheep. Genetic polymorphism has a great influence on the improvement of sheep traits. The aim of this study was to analyze the effect of cadherin 18 (CDH18) gene polymorphisms on growth traits in Hu sheep.
Tianyi Liu, Yazhen Bi, Jingjing Bao, Mingyu Shang, Wenping Hu, Li Zhang   +5 more
wiley   +1 more source

The Evolution of G-quadruplex Structure in mRNA Untranslated Region

Evolutionary Bioinformatics, 2021
The RNA G-quadruplex (rG4) is a kind of non-canonical high-order secondary structure with important biological functions and is enriched in untranslated regions (UTRs) of protein-coding genes. However, how rG4 structures evolve is largely unknown.
Ting Qi, Yuming Xu, Tong Zhou, Wanjun Gu
doaj   +1 more source

Erythrocyte complement receptor 1 (CR1) expression level is not associated with polymorphisms in the promoter or 3' untranslated regions of the CR1 gene [PDF]

, 2006
Complement receptor 1 (CR1) expression level on erythrocytes is genetically determined and is associated with high (H) and low (L) expression alleles identified by a HindIII restriction fragment-length polymorphism (RFLP) in intron 27 of the CR1 gene ...
Cockburn I.A., Cockburn I.A., Funkhouser T., Kim J.H., Moulds J.M., Rowe J.A., Tournamille C., Vik D.P., Xiang L.   +8 more
core   +1 more source

Regulation of CCN1 via the 3′-untranslated region [PDF]

Journal of Cell Communication and Signaling, 2013
The 3'-untranslated region (UTR) is known to be a critical regulator of post-transcriptional events that determine the gene expression at the RNA level. The gene CCN1 is one of the classical members of the matricellular CCN family and is involved in a number of biological processes during mammalian development.
Yosuke Nakagawa, Aya Maeda, Yurika Murase, Kumi Sumiyoshi, Satoshi Kubota, Masaharu Takigawa, Takashi Nishida, Chikako Hara, Masanao Minato   +8 more
openaire   +3 more sources

UTRme: A Scoring-Based Tool to Annotate Untranslated Regions in Trypanosomatid Genomes

Frontiers in Genetics, 2018
Most signals involved in post-transcriptional regulatory networks are located in the untranslated regions (UTRs) of the mRNAs. Therefore, to deepen our understanding of gene expression regulation, delimitation of these regions with high accuracy is ...
Santiago Radío, Santiago Radío, Rafael Sebastián Fort, Rafael Sebastián Fort, Beatriz Garat, José Sotelo-Silveira, José Sotelo-Silveira, Pablo Smircich, Pablo Smircich   +8 more
doaj   +1 more source

cDNA Cloning Demonstrates the Expression of Pregnancy-Specific Glycoprotein Genes, a Subgroup of the Carcinoembryonic Antigen Gene Family, in Fetal Liver [PDF]

, 1989
The pregnancy-specific glycoprotein (PSG) genes constitute a subgroup of the carcinoembryonic antigen (CEA) gene family. Here we report the cloning of four cDNAs coding for different members of the PSG family from a human fetal liver cDNA library.
Thompson, John A., Weiss, Martina, Zimmermann, Wolfgang   +2 more
core   +1 more source

High-efficiency Generation of Multiple Short Noncoding RNA in B-cells and B-cell-derived Extracellular Vesicles

Molecular Therapy: Nucleic Acids, 2015
Short noncoding (snc)RNAs are important new players in the landscape of biologics with therapeutic potential. Recently, we reported on a new method for the synthesis and delivery of snc RNA in B-cells transfected with plasmid DNA.
Gonzalo Almanza, Maurizio Zanetti
doaj   +1 more source