Results 21 to 30 of about 164,097 (264)
The Roles of the 5′ and 3′ Untranslated Regions in Human Astrovirus Replication
Viruses, 2023 Astroviruses are small nonenveloped single-stranded RNA viruses with a positive sense genome. They are known to cause gastrointestinal disease in a broad spectrum of species.
Nicole Wildi, Torsten Seuberlich
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The androgen receptor messenger RNA: what do we know?
RNA Biology, 2022 The Androgen Receptor (AR), transcriptionally activated by its ligands, testosterone and dihydrotestosterone (DHT), is widely expressed in cells and tissues, influencing normal biology and disease states. The protein product of the AR gene is involved in
Eviania Likos +3 more
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Genetic variants in mRNA untranslated regions [PDF]
WIREs RNA, 2018 Genome Wide Association Studies (GWAS) have mapped thousands of genetic variants associated with complex disease risk and regulating quantitative traits, thus exploiting an unprecedented high‐resolution genetic characterization of the human genome. A small fraction (3.7%) of the identified associations is located in untranslated regions (UTRs), and the
Steri M, Idda ML, Whalen MB, Orru' V
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Selective translation of the measles virus nucleocapsid mRNA by La protein
Frontiers in Microbiology, 2011 Measles, caused by measles virus (MeV) infection, is the leading cause of death in children because of secondary infections attributable to MeV-induced immune suppression.
Yoshihisa eInoue +5 more
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Properties of untranslated regions of the S. cerevisiae genome [PDF]
BMC Genomics, 2009 During evolution selection forces such as changing environments shape the architecture of genomes. The distribution of genes along chromosomes and the length of intragenic regions are basic genomic features known to play a major role in the regulation of gene transcription and translation.In this work we perform the first large scale analysis of the ...
Tuller Tamir +2 more
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Viruses, 2019 The 5′ untranslated region (UTR) of the RNA genomes of enteroviruses possesses an internal ribosome entry site (IRES) that directs translation of the mRNA by binding to ribosomes.
Yuki Furuse +3 more
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Tumor Biology, 2017 X-linked inhibitor of apoptosis protein functions as an intrinsic regulator of apoptosis by inhibition of caspase activity and possesses a pivotal role in human cancer development and progression.
Wen-Yong Wu +4 more
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Novel Dengue Virus Type 1 from Travelers to Yap State, Micronesia
Emerging Infectious Diseases, 2006 Dengue virus type 1 (DENV-1), which was responsible for the dengue fever outbreak in Yap State, Micronesia, in 2004, was isolated from serum samples of 4 dengue patients in Japan. Genome sequencing demonstrated that this virus belonged to genotype IV and
Yoko Nukui +6 more
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Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States
Cell Reports, 2020 Summary: Loading of skeletal muscle changes the tissue phenotype reflecting altered metabolic and functional demands. In humans, heterogeneous adaptation to loading complicates the identification of the underpinning molecular regulators.
Tanner Stokes +13 more
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Dom34 Rescues Ribosomes in 3′ Untranslated Regions [PDF]
Cell, 2014 Ribosomes that stall before completing peptide synthesis must be recycled and returned to the cytoplasmic pool. The protein Dom34 and cofactors Hbs1 and Rli1 can dissociate stalled ribosomes in vitro, but the identity of targets in the cell is unknown. Here, we extend ribosome profiling methodology to reveal a high-resolution molecular characterization
Guydosh, Nicholas R., Green, Rachel
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