The Roles of the 5′ and 3′ Untranslated Regions in Human Astrovirus Replication [PDF]
Viruses, 2023 Astroviruses are small nonenveloped single-stranded RNA viruses with a positive sense genome. They are known to cause gastrointestinal disease in a broad spectrum of species.
Nicole Wildi, Torsten Seuberlich
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Identification and Cross-Characterisation of Artificial Promoters and 5′ Untranslated Regions in Vibrio natriegens [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Vibrio natriegens has recently gained attention as a novel fast-growing bacterium in synthetic biology applications. Currently, a limited set of genetic elements optimised for Escherichia coli are used in V.
Lisa Tietze +3 more
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The untranslated regions of genes from Trypanosoma cruzi: perspectives for functional characterization of strains and isolates [PDF]
Memorias do Instituto Oswaldo Cruz, 2006 The sequencing of Trypanosoma cruzi genome has been completed and a great deal of information is now available. However, the organization of protozoa genomes is somewhat elusive and much effort must be applied to reveal all the information coded in the ...
Adeilton Brandão
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Genetic variants in mRNA untranslated regions [PDF]
WIREs RNA, 2018 Genome Wide Association Studies (GWAS) have mapped thousands of genetic variants associated with complex disease risk and regulating quantitative traits, thus exploiting an unprecedented high‐resolution genetic characterization of the human genome. A small fraction (3.7%) of the identified associations is located in untranslated regions (UTRs), and the
Steri M, Idda ML, Whalen MB, Orru' V
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3′untranslated regions: regulation at the end of the road [PDF]
Current Genetics, 2018 Post-transcriptional gene regulation in bacteria plays a major role in the adaptation of bacterial cells to the changing conditions encountered in the environment. In bacteria, most of the regulation at the level of mRNA seems to be targeting the 5'untranslated regions where accessibility to the ribosome-binding site can be modulated to alter gene ...
Youssef El Mouali, Carlos Balsalobre
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Untranslated Regions of a Mobile Transcript Mediate RNA Metabolism [PDF]
Plant Physiology, 2009 BEL1-like transcription factors are ubiquitous in plants and interact with KNOTTED1 types to regulate numerous developmental processes. In potato (Solanum tuberosum subsp. andigena), the BEL1-like transcription factor StBEL5 and its Knox protein partner regulate tuber formation by targeting genes that control growth.
Banerjee, Anjan K. +2 more
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Massively parallel functional annotation of 3′ untranslated regions [PDF]
Nature Biotechnology, 2014 Functional characterization of noncoding sequences is crucial for understanding the human genome and learning how genetic variation contributes to disease. 3' untranslated regions (UTRs) are an important class of noncoding sequences, but their functions remain largely uncharacterized.
Zhao, Wenxue +5 more
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Evolution of the influenza A virus untranslated regions
Infection, Genetics and Evolution, 2011 In case of the influenza virus, untranslated regions are considered to possess plural functions. The specific packaging model suggests that each of eight segments contains a unique "packaging signal", situated within the untranslated region and coding regions at the 5' and 3' ends of the genomic RNA. In addition to packaging signal, UTRs play key roles
Yuki Furuse, Hitoshi Oshitani
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Association of Dengue Virus Serotypes 1&2 with Severe Dengue Having Deletions in Their 3′Untranslated Regions (3′UTRs) [PDF]
Microorganisms, 2023 Dengue virus infections are recorded as hyper-endemic in many countries, including India. Research pertaining to the reasons for frequent outbreaks and severe dengue is ongoing.
Deepti Maisnam +3 more
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Maize Anther Development Involves Translated Open Reading Frames From 3′ Untranslated Regions [PDF]
Advanced ScienceFew studies have explored the functions of peptides encoded by open reading frames (ORFs) in annotated noncoding regions, particularly the 3′ untranslated regions (3′ UTRs).
Chunyu Wang +8 more
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