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IDENTIFICATION OF SHORTENED 3′ UNTRANSLATED REGIONS FROM EXPRESSION ARRAYS
Journal of Bioinformatics and Computational Biology, 2012Cancer cells have been recently shown to express high level of short 3′UTR isoforms that can escape miRNA-mediated regulation. We present here a computational procedure for systematically identifying shortened 3′UTRs by Affymetrix 3′ microarrays. The advantage of this technology compared to more recent and promising ones such as exon arrays and RNA ...
LOREDANA MARTIGNETTI +2 more
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Regulation of gene expression by alternative untranslated regions
Trends in Genetics, 2006The untranslated regions of mRNAs can determine gene expression by influencing mRNA stability and translational efficiency. Recent reports show that gene expression can be regulated by the differential use of alternative untranslated regions. Tissue-specific expression of transcripts that have different untranslated regions (UTRs) can control protein ...
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Bioinformatics Approaches for Studying Untranslated Regions of mRNAs
2008Interactions between RNA-binding proteins and cis-acting elements in the 5'- and 3'-untranslated regions (UTRs) of transcripts are responsible for regulating essential biological activities, such as mRNA localization, mRNA turnover, and translation efficiency.
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The molecular basis for cellular function of intrinsically disordered protein regions
Nature Reviews Molecular Cell Biology, 2023Alex S Holehouse, Birthe B Kragelund
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Lake and drained lake basin systems in lowland permafrost regions
Nature Reviews Earth & Environment, 2022Benjamin Jones +2 more
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