Results 11 to 20 of about 32,245 (190)

Transcription initiation at a consensus bacterial promoter proceeds via a ‘bind-unwind-load-and-lock’ mechanism

eLife, 2021
Transcription initiation starts with unwinding of promoter DNA by RNA polymerase (RNAP) to form a catalytically competent RNAP-promoter complex (RPo). Despite extensive study, the mechanism of promoter unwinding has remained unclear, in part due to the ...
Abhishek Mazumder, Richard H Ebright, Achillefs N Kapanidis   +2 more
doaj   +1 more source

Identification of the Unwinding Region in the Clostridioides difficile Chromosomal Origin of Replication

Frontiers in Microbiology, 2020
Faithful DNA replication is crucial for viability of cells across all kingdoms. Targeting DNA replication is a viable strategy for inhibition of bacterial pathogens.
Ana M. Oliveira Paiva, Ana M. Oliveira Paiva, Erika van Eijk, Annemieke H. Friggen, Christoph Weigel, Wiep Klaas Smits, Wiep Klaas Smits   +6 more
doaj   +1 more source

Adaptive Sliding Mode Attitude Tracking Control for Rigid Spacecraft Considering the Unwinding Problem

Mathematics, 2023
Based on the unwinding problem caused by the dual valued property of the quaternion description method, this paper designs an anti-unwinding sliding mode adaptive attitude tracking control with external disturbances and inertia matrix uncertainty.
Baoyu Huo, Mingjun Du, Zhiguo Yan
doaj   +1 more source

Mutations altering the interplay between GkDnaC helicase and DNA reveal an insight into helicase unwinding. [PDF]

PLoS ONE, 2011
Replicative helicases are essential molecular machines that utilize energy derived from NTP hydrolysis to move along nucleic acids and to unwind double-stranded DNA (dsDNA).
Yu-Hua Lo, Shih-Wei Liu, Yuh-Ju Sun, Hung-Wen Li, Chwan-Deng Hsiao   +4 more
doaj   +1 more source

Sliding Mode Compensation Control for Diaphragm Tension in Unwinding Process of Lithium Battery Diaphragm Slitting Machine

IEEE Access, 2020
In order to solve the problem of tension control in the actual unwinding process of the lithium battery diaphragm slitting machine, the dynamic model of diaphragm and slitting machine unwinding system is constructed in this paper based on the diaphragm ...
Cheng Jiang, Heng-Sheng Wang, Li-Wei Hou, Liang-Liang Jiang   +3 more
doaj   +1 more source

Amidst multiple binding orientations on fork DNA, Saccharolobus MCM helicase proceeds N-first for unwinding

eLife, 2019
DNA replication requires that the duplex genomic DNA strands be separated; a function that is implemented by ring-shaped hexameric helicases in all Domains.
Himasha M Perera, Michael A Trakselis
doaj   +1 more source

Design and experiments of an automatic pipe winding machine

Journal of Agricultural Engineering, 2023
To solve the time-consuming and laborious problem of manual winding and unwinding water pipes by field workers during irrigation or pesticide spraying in agricultural production, an automatic pipe winding machine for winding and unwinding water pipes ...
Yanmei Meng, Tingting Zhang, Jin Wei, Jinlai Zhang, Xulei Zhai   +4 more
doaj   +1 more source

Modernization of the brake system of unwinding on rope machines

Литьë и металлургия, 2021
In order to reduce the cost of producing metal cord in the hardware shops of OJSC “BSW” – the Management Company of the Holding “BMC”, work is underway to modernize and select materials for replaceable technological equipment.
S. S. Konovalchuk, I. M. Livshits
doaj   +1 more source

A NEW WINCH CONSTRUCTION FOR SMOOTH CABLE WINDING/UNWINDING

Facta Universitatis. Series: Mechanical Engineering, 2017
New constructive solutions of the winches for single-row radial multi-layered cable smooth winding/unwinding are described. Two new structural solutions of winches are defined.
Mirjana Filipović, Ljubinko Kevac
doaj   +1 more source

Two opposite abilities of the infectious bronchitis virus helicase Nsp13: separating the duplex and promoting the annealing of single-stranded nucleic acid

Frontiers in Veterinary Science
Genome replication is a key step in the coronavirus life cycle and requires the involvement of a range of virally encoded non-structural proteins. The non-structural protein 13 (Nsp13) of coronaviruses is a highly conserved helicase and is considered an ...
Chengcheng Wu, Lihan Tao, Haiqin Li, Cong Huang, Yanbing Zeng   +4 more
doaj   +1 more source