Results 31 to 40 of about 32,245 (190)
miRNA-like duplexes as RNAi triggers with improved specificity
Frontiers in Genetics, 2012 siRNA duplexes, the most common triggers of RNA interference, are first loaded into an Argonaute (Ago) protein and then undergo unwinding via passenger strand cleavage, which requires the slicer activity of the Ago protein.
Juan G. Betancur +5 more
doaj +1 more source
The Cellular Functions and Molecular Mechanisms of G-Quadruplex Unwinding Helicases in Humans
Frontiers in Molecular Biosciences, 2021 G-quadruplexes (G4s) are stable non-canonical secondary structures formed by G-rich DNA or RNA sequences. They play various regulatory roles in many biological processes.
Yang Liu +11 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source
Shock in the Yarn during Unwinding from Packages
Abstract and Applied Analysis, 2013 Tension in the yarn and its oscillations during the over-end unwinding of the yarn from stationary packages depend on the unwinding speed, the shape and the winding type of the package, the air drag coefficient, and also the coefficient of friction ...
Stanislav Praček +2 more
doaj +1 more source
Positively Charged Polymer‐Brush MOFs for Large‐Area, Pressure‐Resistant Gas Separation Membranes
Advanced Materials, EarlyView.A universal POPA strategy enables positively charged polymer‐brush MOFs with self‐adaptive interfacial interlocking to resist aggregation under fast processing. This design ensures seamless dispersion within large‐area selective layers, achieving 1 m‐wide roll‐to‐roll fabrication of pressure‐resistant MMCMs with tunable CO2 separation performance ...
Yi Yang +11 more
wiley +1 more source
Helicase promotes replication re-initiation from an RNA transcript
Nature Communications, 2018 During DNA replication, replicative helicases play an essential role for DNA unwinding to occur. Here the authors find that bacteriophage T7 helicase is also involved in replication re-initiation by interacting with a non-replicating DNAP and increasing ...
Bo Sun +5 more
doaj +1 more source
iScience, 2022 Summary: The RecQ family of helicases are important for maintenance of genomic integrity. Although functions of constructive subdomains of this family of helicases have been extensively studied, the helical hairpin (HH) in the RecQ-C-terminal domain (RQC)
Jianbing Ma +10 more
doaj +1 more source
Advanced Materials Technologies, EarlyView.Liquid metal additives are processed in elastomer host resulting in highly conductive and stretchable composites. The material functions as a piezoresistive sensor with minimal drift, low stiffness, and enhanced operating range. The film can replace wires to charge a mobile phone at ∼350% strain and monitors bodily motion in real‐time via a portable ...
Patryk Wojciak +3 more
wiley +1 more source
Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation
Advanced Science, 2020 RNA helicase DDX21 plays vital roles in ribosomal RNA biogenesis, transcription, and the regulation of host innate immunity during virus infection. How DDX21 recognizes and unwinds RNA and how DDX21 interacts with virus remain poorly understood.
Zijun Chen +19 more
doaj +1 more source
Helix Alignment, Chevrons, and Edge Dislocations in Twist‐Bend Ferroelectric Nematics
Advanced Science, EarlyView.The recently discovered twist‐bend ferroelectric nematic (NTBF) is the new member of the multiferroic family, representing a fluid with an oblique helicoidal (heliconical) periodic structure of spontaneous electric polarization. The work presents a thorough exploration of the material properties of this phase, how the periodic modulation of ...
Bijaya Basnet +8 more
wiley +1 more source