Intracellular Uropathogenic E. coli Exploits Host Rab35 for Iron Acquisition and Survival within Urinary Bladder Cells. [PDF]
Recurrent urinary tract infections (UTIs) caused by uropathogenic E. coli (UPEC) are common and morbid infections with limited therapeutic options. Previous studies have demonstrated that persistent intracellular infection of bladder epithelial cells ...
Neha Dikshit +9 more
doaj +13 more sources
Single-cell analysis reveals an important role of CD137L+ macrophages in the host response to uropathogenic Escherichia coli infection in the bladder. [PDF]
Uropathogenic Escherichia coli (UPEC) typically trigger rapid and robust innate immune responses in the bladder. In order to identify the key facets of the host response that influence pathogen clearance and tissue damage, single-cell RNA sequencing was ...
Yaxiao Liu +11 more
doaj +2 more sources
Analysis of Human miRNA Derived From Bladder Epithelial Cells Infected With Uropathogenic Escherichia coli. [PDF]
ABSTRACT MicroRNAs (miRNAs) have been shown to regulate many cellular processes and to play a role in host‐pathogen interactions. However, the role of miRNA in urinary tract infection (UTI) remains unclear. The aim of this study was to analyze and compare miRNAs from supernatants of human bladder epithelial cells infected with ESBL‐producing (ESBL019 ...
Persson K, Demirel I, Rangel I, Kruse R.
europepmc +2 more sources
Detection of fimH virulence gene in uropathogenic Escherichia coli Using PCR [PDF]
Urinary tract infections (UTIs) are one of main health problems caused by many microorganisms, including uropathogenic Escherichia coli (UPEC). The virulence factors are important in colonization of UPEC, extra-intestinal survival, and creation of ...
Rawan Amer Fadhil
doaj +1 more source
A Glimpse into the Resistant Pattern of Uropathogens: An Overview
Urinary tract infection (UTI) poses a serious health issue for all age groups from neonates to geriatric age groups. Majority of the women experience urinary tract infections once in their lifetime.
Monalisa Debbarma +4 more
doaj +1 more source
Background: The ability of Escherichia coli to build biofilms leads to the development of numerous diseases and makes their removal challenging. In addition to being the most common cause of urinary tract infections (UTIs), E.
Dina Hassan Abed Abbood +1 more
doaj +1 more source
How Does Biological Sex Impact Mucosal Bacterial Infection? Mucosal Defenses and Bacterial Detection. [PDF]
ABSTRACT Urinary tract infections possess substantial sex disparities in the incidence, immune response, and progression of infection. Some of these distinctions may be due to sexual dimorphism in mucosal barriers or sex differences in the initial immune response to infection.
Ramirez Finn L, Ingersoll MA.
europepmc +2 more sources
Enteroaggregative Escherichia coli is associated with antibiotic resistance and urinary tract infection symptomatology [PDF]
Background Uropathogenic Escherichia coli (UPEC) is the causative agent of uncomplicated urinary tract infections (UTIs) in ambulatory patients. However, enteroaggregative E.
Verónica I. Martínez-Santos +6 more
doaj +2 more sources
Recurrent urinary tract infections (UTIs) are associated primarily with the ability of Escherichia coli to form biofilms. The interaction of neutrophils, factors of innate immunity, with microorganisms in biofilms is difficult compared to planktonic ...
I. L. Maslennikova +2 more
doaj +1 more source
Enteroaggregative Escherichia coli (EAEC) comprises an important diarrheagenic pathotype, while uropathogenic E. coli (UPEC) is the most important agent of urinary tract infection (UTI). Recently, EAEC virulence factors have been detected in E.
Paulo A. Schüroff +8 more
doaj +1 more source

