Results 91 to 100 of about 734,348 (361)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Characterization and Efficient Search of Non-Elementary Trapping Sets of LDPC Codes with Applications to Stopping Sets

, 2018
In this paper, we propose a characterization for non-elementary trapping sets (NETSs) of low-density parity-check (LDPC) codes. The characterization is based on viewing a NETS as a hierarchy of embedded graphs starting from an ETS.
Banihashemi, Amir H., Hashemi, Yoones
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Properties of virtual MIMO signal and interference in cooperation cognitive networks

Tongxin xuebao, 2012
A virtual MIMO scheme based on cooperation of the prim and secondary users was proposed in the wireless cognitive networks.The tight upper and lower bounds about the complimentary cumulative distribution function of the virtual MIMO signal and ...
Xu BAO, Tie-cheng SONG, Lian-feng SHEN
doaj   +2 more sources

Bounds on the Capacity of the Relay Channel with Noncausal State Information at Source

, 2010
We consider a three-terminal state-dependent relay channel with the channel state available non-causally at only the source. Such a model may be of interest for node cooperation in the framework of cognition, i.e., collaborative signal transmission ...
2010 IEEE International Symposium on Information Theory. ISIT 2010, Piantanida, P., Shamai, S., Vandendorpe, Luc, Zaidi, Abdellatif   +4 more
core   +5 more sources

Upper bounds of root discriminant lower bounds [PDF]

Pacific Journal of Mathematics, 2015
The main goal of the paper is to study the existence of families of number fields with small root discriminant \(rd_K=|d_K|^{1/n_K}, n_K=[K:\mathbb{Q}]\) and additional restrictions on the number of real places \(r_1(K)\). Under the generalized Riemann hypothesis, the author proves that, fixing a fraction of the form \(a/(3^b m)\in [0,1]\cup \mathbb{Q},
openaire   +2 more sources

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

New bounds for the minimum eigenvalue of 𝓜-tensors

Open Mathematics, 2017
A new lower bound and a new upper bound for the minimum eigenvalue of an 𝓜-tensor are obtained. It is proved that the new lower and upper bounds improve the corresponding bounds provided by He and Huang (J. Inequal.
Zhao Jianxing, Sang Caili
doaj   +1 more source

A Novel Approach for Searching the Upper/Lower Bounds of Uncertainty Parameters in Microgrids

Energies, 2018
In this study, a novel method based on μ analysis is presented to search for the upper/lower bounds of uncertainty parameters in microgrids (MGs).
Xiaojun Ding, Kaicheng Li, Yuanzheng Li, Delong Cai, Yi Luo, Youli Dong   +5 more
doaj   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source