Results 81 to 90 of about 734,348 (361)
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Upper and Lower Bounds for Ranks of the Matrix Expression X-XAX
Abstract and Applied Analysis, 2013 We consider the question of how to take X such that the nonlinear matrix expression X-XAX attains its maximal and minimal possible ranks.
Zhiping Xiong
doaj +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Sharp Bounds for the Signless Laplacian Spectral Radius in Terms of Clique Number [PDF]
, 2012 In this paper, we present a sharp upper and lower bounds for the signless Laplacian spectral radius of graphs in terms of clique number. Moreover, the extremal graphs which attain the upper and lower bounds are characterized.
Abraham Berman +5 more
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Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Upper and lower bounds for a reactive-diffuse system with Arrhenius kinetics
International Journal of Mathematics and Mathematical Sciences, 2006 Comparison arguments are used to study a problem in combustion theory consisting of a nonlinear parabolic equation together with initial and boundary conditions. Upper and lower bounds for the problem are constructed.
Mohammed Al-Refai, Qutaibeh Katatbeh
doaj +1 more source
On a unified integral operator for φ-convex functions
Advances in Difference Equations, 2020 Integral operators have a very vital role in diverse fields of science and engineering. In this paper, we use φ-convex functions for unified integral operators to obtain their upper bounds and upper and lower bounds for symmetric φ-convex functions in ...
Young Chel Kwun +4 more
doaj +1 more source
A Sharp Double Inequality for the Inverse Tangent Function [PDF]
, 2013 The inverse tangent function can be bounded by different inequalities, for example by Shafer's inequality. In this publication, we propose a new sharp double inequality, consisting of a lower and an upper bound, for the inverse tangent function.
Alirezaei, Gholamreza
core +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
A Convex Formulation for Mixed Regression with Two Components: Minimax Optimal Rates [PDF]
, 2015 We consider the mixed regression problem with two components, under adversarial and stochastic noise. We give a convex optimization formulation that provably recovers the true solution, and provide upper bounds on the recovery errors for both arbitrary ...
Caramanis, Constantine +2 more
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