Results 91 to 100 of about 3,463,486 (343)
PLoS ONE, 2015 Diagnostic ureterorenoscopy is powerful tool to confirm upper tract urothelial cancer (UTUC). However, URS and associated manipulation may be related to the risk of intravesical recurrence (IVR) following radical nephroureterectomy (RNU).
H. Sung +7 more
semanticscholar +1 more source
Oscillating magnetic field disrupts magnetic orientation in Zebra finches, Taeniopygia guttata
, 2009 Background Zebra finches can be trained to use the geomagnetic field as a directional cue for short distance orientation. The physical mechanisms underlying the primary processes of magnetoreception are, however, largely unknown.
Wiltschko, Wolfgang +21 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Percutaneous nephroscopic resection of pyelocaliceal transitional cell carcinoma in solitary kidney
Urology Annals, 2014 Percutaneous approaches to upper tract urothelial cancers have been performed in patients unsuitable for radical nephroureterectomy. We present two cases of transitional cell carcinoma involving the renal pelvis in either functional or anatomical ...
Bo Yang, Weibing Sun
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Huli yanjiu, 2015 AbstractObjective：To probe into the influence of Ultra early zero docking upper limb rehabilitation gymnastics on shoulder joint function rehabilitation for breast cancer patients after modified radical mastectomy.Methods：To select 130 cases patients ...
刘学朴 +5 more
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Cancer Management and Research, 2020 Yun-Ren Li,1 Kai-Jie Yu,1 Ying-Hsu Chang,2 Po-Hung Lin,1 I-Hung Shao,1 Hung-Cheng Kan,1 Yuan-Cheng Chu,1 Cheng-Keng Chuang,1 See-Tong Pang,1 Chung-Yi Liu2 1Division of Urology, Department of Surgery, Chang Gung Memorial Hospital and Chang Gung University,
Li YR +9 more
doaj