Results 81 to 90 of about 145,867 (288)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

XIX. Yüzyılın İkinci Yarısında Anadolu'daki Ermeni Terörü (Diyarbakır, Arapgîr, Harput, Merzifon, Havza, Amasya ve Malatya'da Meydana Gelen Ermeni Ayaklanmaları Hakkında Bir Lâyiha)

open access: yesBelgeler, 2008
Ermeni meselesi ve pek çok konuya ilişkin arşivlerimizde zengin bilgiler bulunmaktadır. Nitekim bu haliyle arşivlerimiz bütün dünya devletlerini yakından ilgilendiren bir hüviyettedir.
Ahmet Halaçoğlu
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Approaches to the review of the Khotyn Uprising in 1919 in soviet and contemporary Ukrainian historiography

open access: yesНауковий вісник Чернівецького національного університету імені Юрія Федьковича. Історія, 2019
The Khotyn Uprising was an event that became one of the most striking pages in the history of the region in the XX century. Considerable attention was paid to the study of the history of this issue during the Soviet period, but interpretation of the ...
Tetyana Dubitska
doaj   +1 more source

Tensions of colonial punishment: perspectives on recent developments in the study of coercive networks in Asia, Africa and the Caribbean [PDF]

open access: yes, 2000
The study of penal practices in colonised parts of Asia, Africa, Latin America, the Indian Ocean and the Caribbean has recently witnessed a significant shift.
Altink   +77 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

PRASA OKRESU POWSTANIA WARSZAWSKIEGO. „BIULETYN INFORMACYJNY” I JEGO STRUKTURA GATUNKOWA

open access: yesCivitas et Lex, 2018
The presented paper concerns press in the period of the Warsaw Uprising, especially “Biuletyn Informacyjny”. Polish underground editing movement was the greatest amongst European countries covered by the World War II.
Wioleta Wróbel
doaj   +1 more source

Speech by H.E. Amani Abeid Karume former President of Zanzibar on recent developments in North Africa; impact on the Arab World, Africa and the world at large, lessons learned [PDF]

open access: yes, 2011
This is the archive of a speech on developments in North Africa given by President Karume of Zanzibar, APC's 7th President in Residence, on March 10 ...
Karume, H.E. Amani Abeid
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

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