UPSIT subitems may predict motor progression in Parkinson’s disease
BackgroundThe relationship between hyposmia and motor progression is controversial in Parkinson’s disease (PD). The aim of this study was to investigate whether preserved identification of Chinese-validated University of Pennsylvania Smell Identification
Yu-Hsuan Lin +6 more
doaj +3 more sources
The Middle Turbinate Resection and Its Repercussion in Olfaction with the University of Pennsylvania Smell Identification Test (UPSIT) [PDF]
Introduction Nasal obstruction is a common complaint, and, for some, the middle turbinate resection is still a controversial issue among the surgical options due to the possibility of deleterious effects on olfaction. The University of Pennsylvania smell
Fernando Cesar Mariano +3 more
doaj +4 more sources
Olfactory testing in children using objective tools: Comparison of Sniffin’ Sticks and University of Pennsylvania Smell Identification Test (UPSIT) [PDF]
Background Detection of olfactory dysfunction is important for fire and food safety. Clinical tests of olfaction have been developed for adults but their use in children has been limited because they were felt to be unreliable in children under six years
Sarah C Hugh +6 more
doaj +4 more sources
Development of a simplified smell test to identify Parkinson’s disease using multiple cohorts, machine learning and item response theory [PDF]
To develop a simplified smell test for identifying patients with Parkinson’s disease (PD), we reevaluated the Sniffin’-Sticks-Identification-Test (SST-ID) and University-of-Pennsylvania-Smell-Identification-Test (UPSIT), using three case-control studies.
Juan Li +17 more
doaj +2 more sources
Importance of Smell Loss to Patients With Chronic Rhinosinusitis With Nasal Polyps: Options for Management and Recovery. [PDF]
ABSTRACT Primary diffuse type 2‐dominant chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory disease of the nasal cavity and paranasal sinuses associated with significant morbidity. Impaired sense of smell is a cardinal symptom of CRSwNP and one of the most burdensome for patients, impacting quality of life, mental health, and even ...
Higgins TS +9 more
europepmc +2 more sources
The Utility of Olfactory Testing to Discriminate Parkinson's Disease From Diagnostic Mimics: A Systematic Review and Meta-Analysis. [PDF]
ABSTRACT Background Hyposmia is present in most patients with Parkinson's disease (PD), whereas olfaction is usually preserved in its diagnostic mimics. To address the limited evidence from smaller studies, we conducted a meta‐analysis on the diagnostic accuracy of olfactory testing in differentiating PD from clinical look‐alikes.
Theyer C +11 more
europepmc +2 more sources
Longitudinal Neuroimaging Reveals Divergent Clinical Associations of Glymphatic Dysfunction and Dopaminergic Degeneration in Parkinson's Disease. [PDF]
Both DTI‐ALPS and DAT‐SBR index in patients with PD were significantly lower compared to Healthy Controls, with further reductions observed at the follow‐up. Both DTI‐ALPS and DAT‐SBR index in PD showed significant correlation with different clinical measures, while no significant correlation was observed between these two index.
Liu T +7 more
europepmc +2 more sources
Screening performance of abbreviated versions of the UPSIT smell test [PDF]
ABSTRACTBackgroundHyposmia features in several neurodegenerative conditions, including Parkinson’s disease (PD). The University of Pennsylvania Smell Identification Test (UPSIT) is a widely used screening tool for detecting hyposmia, but is time-consuming and expensive when used on a large scale.MethodsWe assessed shorter subsets of UPSIT items for ...
Joseph, T +8 more
openaire +4 more sources
The shelf life of the university of pennsylvania smell identification test (UPSIT) [PDF]
AbstractThe shelf life of the University of Pennsylvania Smell Identification Test was studied by comparing, using a within‐subjects design, scores for tests manufactured within 2 months of the time of testing, 2½ years before the time of testing, and 4 years before testing.
R L, Doty, U, Agrawal
openaire +2 more sources
Long-Term Test–Retest Reliability of the UPSIT in Cognitively Intact Older Adults [PDF]
Abstract The objective of this study was to determine the long-term test–retest reliability of the University of Pennsylvania Smell Identification Test (UPSIT), and its individual items, in cognitively intact older adults. A community sample of older adults received a neuropsychological test battery, including the 12-item, 6-trial ...
Seonjoo Lee +6 more
openaire +2 more sources

