Results 81 to 90 of about 3,377 (180)

Odor identification impairment and cholinesterase inhibitor treatment in Alzheimer's disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021
Introduction This study evaluated acute change in odor identification following atropine nasal spray challenge, and 8‐week change in odor identification ability, as a predictor of long‐term improvement in patients with mild to moderate Alzheimer's ...
Jeffrey N. Motter, Xinhua Liu, Min Qian, Hannah R. Cohen, Davangere P. Devanand   +4 more
doaj   +1 more source

67702 At-Home Screening Tool for Anosmia

Journal of Clinical and Translational Science, 2021
IMPACT: By developing and validating a simple and cost-effective at-home screening tool for loss of smell, we can efficiently detect infection with COVID-19, neuropsychiatric disease such as Alzheimer’s, and post-operative smell loss.
Shruti Gupta, Dorina Kallogjeri, Jay F Piccirillo   +2 more
doaj   +1 more source

Validation of the local applicability of the ‘TIB’ Olfactory Test Device in the era of COVID-19

Journal of International Medical Research, 2022
Objective To evaluate the validity and test–retest reliability of the novel ‘TIB’ Olfactory Test Device (TIB) and to determine its normative values. Methods The study stratified the study subjects into normosmic, hyposmic and anosmic groups according to ...
Rong-San Jiang, Jing-Jie Wang, Kai-Li Liang, Kai-Hsiang Shih   +3 more
doaj   +1 more source

What does it mean when the pleasant smells come and go? Correlation between UPSIT odor identification status and fluctuation of non-motor symptoms in Parkinson's disease. [PDF]

Acta Neurol Belg
Abstract Parkinson’s disease (PD) is characterized by motor and non-motor symptoms, including olfactory dysfunction. Prior studies have shown that olfaction deteriorates with disease progression, however fluctuations in olfaction and related PD symptoms have been less explored.
Lei HB, Fang TC, Lin YH, Chiu SC, Chang MH, Guo YJ.   +5 more
europepmc   +3 more sources

Serum p‐tau217 Is a Prognostic Indicator of Cognitive Impairment in Idiopathic REM Sleep Behavior Disorder

Annals of Neurology, Volume 99, Issue 4, Page 912-921, April 2026.
Objective Assess the performance of serum phosphorylated tau 217 (p‐tau217) and neurofilament light chain (NfL) in predicting risk of cognitive impairment or phenoconversion to dementia in individuals with iRBD. Methods We measured serum p‐tau217 and NfL levels by electrochemiluminescence across 4 polysomnographically confirmed iRBD cohorts (n = 300 ...
Shijun Yan, Anis Sahoo, Tanja Zerenner, Kenneth Marek, Michael Sommerauer, Wolfgang Oertel, Michele T. Hu, George K. Tofaris   +7 more
wiley   +1 more source

Odorant normative data for use in olfactory memory experiments: Dimension selection and analysis of individual differences [PDF]

, 2016
The present study reports normative ratings for 200 food and non-food odors. One hundred participants rated odors across measures of verbalisability, perceived descriptive ability,context availability, pleasantness, irritability, intensity ...
Altarriba, Altman, Andrade, Ayabe-Kanamura, Balota, Bensafi, Berglund, Brown, Brysbaert, Cain, Coltheart, Cornell Kärnekull, Dalton, Degel, Distel, Doty, Doty, Doty, Doty, Ebner, Frank, Freiherr, Gilbert, Hay, Henion, Jellinek, Jellinek, Johnson, Johnson, Johnson, Jönsson, Jönsson, Kaeppler, Köster, Larsson, Larsson, Larsson, Larsson, Lawless, Miles, Moberg, Morrison, Nguyen, Oberg, Olsson, Purdon, Rabin, Rabin, Reed, Richardson, Rolls, Savic, Schiffman, Sezille, Stevenson, Sulmont, Uebersax, White, Wood, Yeshurun, Yoon, Yoshida, Zajonc, Zelano, Zucco   +64 more
core   +2 more sources

Comorbid Chronic Rhinosinusitis and Asthma: Shared Risk Factors and Treatment Implications—An EAACI Task Force Report

Allergy, Volume 81, Issue 4, Page 1000-1023, April 2026.
ABSTRACT Chronic rhinosinusitis (CRS) and asthma are prevalent conditions that often coexist. These diseases share common inflammatory mechanisms, such as T‐helper cell 2 (T2)‐high inflammation, driven by interleukin (IL)‐4, IL‐5, and IL‐13 cytokines.
Sanna Toppila‐Salmi, Sietze Reitsma, Valérie Hox, Simon Gane, Philippe Gevaert, Juan Maza‐Solano, Alma Helevä, Ida Sulku, Kaisa Santala, Iiris Kangasniemi, Ludger Klimek, Adam Chaker, Aspasia Karavelia, Michael Rudenko, Oliver Pfaar, Laura Van Gerven, Shaari Ariana, Michele Schiappoli, Marie Lundberg, Jan Hagemann, Ibon Eguíluz‐Gracia, Andre Moreira   +21 more
wiley   +1 more source

The Association of Olfactory Dysfunction With Depression, Cognition, and Disease Severity in Parkinson's Disease

Frontiers in Neurology, 2021
Background: Non-motor subtypes of Parkinson's disease (PD) include the limbic, cognitive, and brainstem phenotype, which may have different pathological pathways with olfaction.
Ting-Chun Fang, Ming-Hong Chang, Ming-Hong Chang, Chun-Pai Yang, Yi-Huei Chen, Ching-Heng Lin   +5 more
doaj   +1 more source

Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients

Clinical &Experimental Allergy, Volume 56, Issue 3, Page 227-242, March 2026.
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna, Christina Morgenstern, Katharina Poglitsch, Tamara Arnoldner, Katharina Gangl, Tina J. Bartosik, Nicholas J. Campion, Aldine Tu, Victoria Stanek, Sven Schneider, Christine Bangert   +10 more
wiley   +1 more source

Dupilumab improved objective and patient-reported outcomes in patients with chronic rhinosinusitis with nasal polyps and complete nasal obstruction [PDF]

Exploration of Asthma & Allergy
Aim: The impact of complete bilateral nasal obstruction [nasal polyp score (NPS) = 8/8] on treatment outcomes in chronic rhinosinusitis with nasal polyps (CRSwNP) is unclear.
Martin Wagenmann, Claus Bachert, Claire Hopkins, Mark Corbett, Jérôme Msihid, Scott Nash, Yamo Deniz, Paul J. Rowe, Harry Sacks, Juby A. Jacob-Nara   +9 more
doaj   +1 more source