Results 171 to 180 of about 76,412 (252)

Tetflupyrolimet shows selectivity for plant dihydroorotate dehydrogenase over Aspergillus orthologs. [PDF]

Sci Rep
Kim SI, Turlapati V, Agashe B, Lu Q, Satagopan S, Sweigard JA, Emptage RP.   +6 more
europepmc   +1 more source

Fluorinated Aminopiperidones as Non‐Glutarimide Thalidomide Analogs: Stereodivergent Synthesis and Validation

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Fluorinated aminopiperidones, designed as non‐glutarimide thalidomide analogs, were synthesized with full regio‐ and stereocontrol. The C*–CF3 used as carbonyl surrogate improved solubility and membrane interactions while abolishing cereblon binding.
Boštjan Adamlje, Tihomir Tomašič, Christian Steinebach, Sebastian Ebeling, Alexander Herrmann, Marcus D. Hartmann, Jessica L. Horner, Kinjal Bhadresha, Cindy H. Chau, William D. Figg, Izidor Sosič, Andrej Emanuel Cotman   +11 more
wiley   +1 more source

On the ozonation of anti-SARS-CoV-2 substances and their nucleoside analogues for mechanistic understanding of the ozone induced transformation using HPLC-ESI-Q-TOF-HRMS. [PDF]

RSC Adv
Bartels I, Hoffmann-Jacobsen K, Schmidt TC, Jaeger M.   +3 more
europepmc   +1 more source

Uracil Ointment [PDF]

, 2020
openaire   +1 more source

The <i>AfldrnA</i> Transcription Factor Is a Pivotal Regulator of the Conidiation-Sclerotial Formation Balance in <i>Aspergillus flavus</i>. [PDF]

J Fungi (Basel)
Abdo-Elgabbar MA, Salim B, Jun SC, Kim YK, Alasmari S, Han KH.   +5 more
europepmc   +1 more source

Effects of thymidylate synthase inhibitors differ in genomic uracilation and mutagenic potential. [PDF]

Life Sci Alliance
Holub E, Papp G, Pálinkás HL, Szajkó MB, Izrael R, Róna G, Vértessy BG, Békési A.   +7 more
europepmc   +1 more source

Myricetin Inhibits <i>Toxoplasma gondii</i> Growth, Alters Intracerebral Cyst Morphology, and Demonstrates Therapeutic Efficacy In Vivo. [PDF]

Cells
Ge CC, He HX, Pei MY, Tang SQ, He W, Bian MM, Pan M, Huang SY.   +7 more
europepmc   +1 more source

Association of DPYD rs4294451, plasma uracil concentration, and sex with 5-fluorouracil exposure in patients with gastrointestinal cancer. [PDF]

Cancer Chemother Pharmacol
Brooks GA, Ness DB, Hourdequin KC, Ripple GH, Amin M, Lord-Halvorson S, Khan WA, Deharvengt SJ, Busque V, Dragnev KH, Zhao W, Tosteson TD, Lewis LD.   +12 more
europepmc   +1 more source

What is in a name? Rethinking SMUG1 in genome maintenance. [PDF]

NAR Cancer
Rudolfova N, Skjetne AM, Montaldo NP, Visnes T, Nilsen HL, Michel M.   +5 more
europepmc   +1 more source