Results 41 to 50 of about 14,080 (252)
Біологічні студії, 2015 For the first time, on the quantum-mechanical level of theory MP2/6-311++G(2df,pd)//B3LYP/6-311++G(d,p), a full set of hydrogen (H)-bonded hetero associates m9Ade·m1Ura in the main tautomeric forms consisting of 18 different structures was obtained ...
D. Plodnik, I. Voiteshenko, D. Hovorun
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Targeted rapid amplification of cDNA ends (T-RACE)-an improved RACE reaction through degradation of non-target sequences [PDF]
, 2010 Amplification of the 5' ends of cDNA, although simple in theory, can often be difficult to achieve. We describe a novel method for the specific amplification of cDNA ends. An oligo-dT adapter incorporating a dUTP-containing PCR primer primes first-strand
Bower, Neil I. +3 more
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Viruses with U-DNA: New Avenues for Biotechnology
Viruses, 2021 Deoxyuridine in DNA has recently been in the focus of research due to its intriguing roles in several physiological and pathophysiological situations. Although not an orthodox DNA base, uracil may appear in DNA via either cytosine deamination or thymine ...
Kinga K. Nagy +2 more
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Acta Chimica Slovenica, 2018 The photocyclodimerization mechanisms of two oxo tautomers of uracil and 6-azauracil were studied at the CC2 level of theory and cc-pVDZ basis functions.
Pavlina Bogomilova Kancheva +1 more
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Pyrimidine salvage in Toxoplasma gondii as a target for new treatment
Frontiers in Cellular and Infection Microbiology, 2023 Toxoplasmosis is a common protozoan infection that can have severe outcomes in the immunocompromised and during pregnancy, but treatment options are limited.
Hamza A. A. Elati +6 more
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Detection of Genomic Uracil Patterns
, 2021 The appearance of uracil in the deoxyuridine moiety of DNA is among the most frequently occurring genomic modifications. Three different routes can result in genomic uracil, two of which do not require specific enzymes: spontaneous cytosine deamination ...
Hajnalka Laura Pálinkás +3 more
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Precluding uracil from DNA [PDF]
, 1996 Two enzymes, dUTP pyrophosphatase and uracil-DNA glycosylase, prevent the misincorporation of uracil into the genome in distinct manners. The atomic structures of these proteins complexed with substrate analogs reveal the structural basis for uracil ...
Vassylyev, Dmitry G, Morikawa, Kosuke
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Synthesis of Uracil-Iodonium(III) Salts for Practical Utilization as Nucleobase Synthetic Modules
Molecules, 2019 Iodonium(III) salts bearing uracil moieties have recently appeared in the literature, but their structural scope and utilization are limited because of their hygroscopic characteristics.
Naoko Takenaga +6 more
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Biochemistry and Biophysics Reports, 2021 Uracil DNA glycosylases are an important class of enzymes that hydrolyze the N-glycosidic bond between the uracil base and the deoxyribose sugar to initiate uracil excision repair.
Avani Mehta +4 more
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