Results 21 to 30 of about 139,089 (266)
Frontiers in Bioengineering and Biotechnology, 2022 Low-lying electronic excited states and their relaxation pathways as well as energetics of the crosslinking reaction between uracil as a model system for pyrimidine-type building blocks of DNA and RNA and benzene as a model system for aromatic groups of ...
Attila Bende +3 more
doaj +1 more source
Synthesis and Evaluation of Some Uracil Nucleosides as Promising Anti-Herpes Simplex Virus 1 Agents
Molecules, 2021 Since herpes simplex virus type 1 (HSV-1) infection is so widespread, several antiviral drugs have been developed to treat it, among which are uracil nucleosides.
Samir Mohamed Awad +3 more
doaj +1 more source
Uracil mustard revisited [PDF]
Cancer, 1999 A patient with diffuse large cell lymphoma who had a complete response lasting 35 years following a 3-day course of uracil mustard stimulated a recall review of patients treated with this oral alkylating agent.Records of patients treated with uracil mustard between 1958 and 1970 were reviewed.
B J, Kennedy +2 more
openaire +2 more sources
Optimisation of the Schizosaccharomyces pombe urg1 expression system [PDF]
, 2013 The ability to study protein function in vivo often relies on systems that regulate the presence and absence of the protein of interest. Two limitations for previously described transcriptional control systems that are used to regulate protein expression
A Yamashita +34 more
core +5 more sources
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020 The most common ways of their chemical modification are used namely, electrophilic and nucleophilic substitution reactions during the purposeful search for active substances among pyrimidines with aromatic properties.
O. V. Velchynska
doaj +1 more source
Synthesis of Some N1-Benzyl -6-(thio and alkyl or aryl thio) Uracil derivatives [PDF]
Kirkuk Journal of Science, 2013 New series of N1-Benzyl -6-(thio derivatives) Uracils have been prepared by reaction of 6-chloro uracil [F3] with benzyl chloride in dimethyl sulphoxide in presence of sodium carbonate to yield N1-Benzyl-6-chloro uracil [F4].Heating of [F4] in ethanol ...
Mohsin Omer Mohammad
doaj +1 more source
Pyrimidine Biosynthesis and Ribonucleoside Metabolism in Species of Pseudomonas
Fermentation, 2023 Pyrimidine biosynthesis and ribonucleoside metabolism in species of Pseudomonas was the focus of this review, in relation to their current taxonomic assignments in different homology groups.
Thomas P. West
doaj +1 more source
Mechanisms of base selection by human single-stranded selective monofunctional uracil-DNA glycosylase [PDF]
, 2009 hSMUG1 (human single-stranded selective monofunctional uracil-DNA glyscosylase) is one of three glycosylases encoded within a small region of human chromosome 12. Those three glycosylases, UNG (uracil-DNA glycosylase), TDG (thymine-DNA glyscosylase), and
Agus Darwanto +63 more
core +3 more sources
Threshold behavior in metastable dissociation of multi-photon ionized thymine and uracil [PDF]
, 2017 Microsecond-timescale HNCO loss has been observed from single-color multi-photon ionized pyrimidine nucleobases in the gas phase. Photon energy thresholds for the metastable channels have been measured at 5.55 ± 0.02 eV for thymine and 5.57 ± 0.02 eV for
da Fonseca Cunha, T. +8 more
core +4 more sources
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source