Results 11 to 20 of about 86,414 (313)
A study of the valence photoelectron spectrum of uracil and mixed water–uracil clusters
The Journal of Chemical Physics, 2023 The valence ionization of uracil and mixed water–uracil clusters has been studied experimentally and by ab initio calculations. In both measurements, the spectrum onset shows a red shift with respect to the uracil molecule, with the mixed cluster characterized by peculiar features unexplained by the sum of independent contributions of the water or ...
Giuseppe Mattioli +15 more
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Frontiers in Bioengineering and Biotechnology, 2022 Low-lying electronic excited states and their relaxation pathways as well as energetics of the crosslinking reaction between uracil as a model system for pyrimidine-type building blocks of DNA and RNA and benzene as a model system for aromatic groups of ...
Attila Bende +3 more
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Synthesis and Evaluation of Some Uracil Nucleosides as Promising Anti-Herpes Simplex Virus 1 Agents
Molecules, 2021 Since herpes simplex virus type 1 (HSV-1) infection is so widespread, several antiviral drugs have been developed to treat it, among which are uracil nucleosides.
Samir Mohamed Awad +3 more
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020 The most common ways of their chemical modification are used namely, electrophilic and nucleophilic substitution reactions during the purposeful search for active substances among pyrimidines with aromatic properties.
O. V. Velchynska
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Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
Pyrimidine Biosynthesis and Ribonucleoside Metabolism in Species of Pseudomonas
Fermentation, 2023 Pyrimidine biosynthesis and ribonucleoside metabolism in species of Pseudomonas was the focus of this review, in relation to their current taxonomic assignments in different homology groups.
Thomas P. West
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Synthesis of Some N1-Benzyl -6-(thio and alkyl or aryl thio) Uracil derivatives [PDF]
Kirkuk Journal of Science, 2013 New series of N1-Benzyl -6-(thio derivatives) Uracils have been prepared by reaction of 6-chloro uracil [F3] with benzyl chloride in dimethyl sulphoxide in presence of sodium carbonate to yield N1-Benzyl-6-chloro uracil [F4].Heating of [F4] in ethanol ...
Mohsin Omer Mohammad
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Uracil-Induced Down-Regulation of the Yeast Uracil Permease [PDF]
Journal of Bacteriology, 1999 ABSTRACT In Saccharomyces cerevisiae the FUR4 -encoded uracil permease catalyzes the first step of the pyrimidine salvage pathway. The availability of uracil has a negative regulatory effect upon its own transport.
K, Séron +3 more
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Frontiers in Microbiology, 2023 The gut microbiota is essential for the growth and development of insects, and the intestinal immune system plays a critical role in regulating the homeostasis of intestinal microorganisms and their interactions with pathogenic bacteria.
Dan Zhao +8 more
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Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase [PDF]
, 2013 Uracil-DNA glycosylase (UDG) compromises the replication strategies of diverse viruses from unrelated lineages. Virally encoded proteins therefore exist to limit, inhibit or target UDG activity for proteolysis.
Cole, Ambrose R. +11 more
core +1 more source