Results 11 to 20 of about 76,412 (252)

Theoretical Study of Light-Induced Crosslinking Reaction Between Pyrimidine DNA Bases and Aromatic Amino Acids

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Low-lying electronic excited states and their relaxation pathways as well as energetics of the crosslinking reaction between uracil as a model system for pyrimidine-type building blocks of DNA and RNA and benzene as a model system for aromatic groups of ...
Attila Bende   +3 more
doaj   +1 more source

Synthesis and Evaluation of Some Uracil Nucleosides as Promising Anti-Herpes Simplex Virus 1 Agents

open access: yesMolecules, 2021
Since herpes simplex virus type 1 (HSV-1) infection is so widespread, several antiviral drugs have been developed to treat it, among which are uracil nucleosides.
Samir Mohamed Awad   +3 more
doaj   +1 more source

Synthesis of new alkyl derivatives of N(1)-(2’-bromo-1’,1’-difluoro-2’-chloroethyl)uracil with potential antitumor activity

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
The most common ways of their chemical modification are used namely, electrophilic and nucleophilic substitution reactions during the purposeful search for active substances among pyrimidines with aromatic properties.
O. V. Velchynska
doaj   +1 more source

Pyrimidine Biosynthesis and Ribonucleoside Metabolism in Species of Pseudomonas

open access: yesFermentation, 2023
Pyrimidine biosynthesis and ribonucleoside metabolism in species of Pseudomonas was the focus of this review, in relation to their current taxonomic assignments in different homology groups.
Thomas P. West
doaj   +1 more source

Synthesis of Some N1-Benzyl -6-(thio and alkyl or aryl thio) Uracil derivatives [PDF]

open access: yesKirkuk Journal of Science, 2013
New series of N1-Benzyl -6-(thio derivatives) Uracils have been prepared by reaction of 6-chloro uracil [F3] with benzyl chloride in dimethyl sulphoxide in presence of sodium carbonate to yield N1-Benzyl-6-chloro uracil [F4].Heating of [F4] in ethanol ...
Mohsin Omer Mohammad
doaj   +1 more source

Effects of the pyrE deletion mutant from Bacillus thuringiensis on gut microbiota and immune response of Spodoptera exigua

open access: yesFrontiers in Microbiology, 2023
The gut microbiota is essential for the growth and development of insects, and the intestinal immune system plays a critical role in regulating the homeostasis of intestinal microorganisms and their interactions with pathogenic bacteria.
Dan Zhao   +8 more
doaj   +1 more source

Uracil-Induced Down-Regulation of the Yeast Uracil Permease [PDF]

open access: yesJournal of Bacteriology, 1999
ABSTRACT In Saccharomyces cerevisiae the FUR4 -encoded uracil permease catalyzes the first step of the pyrimidine salvage pathway. The availability of uracil has a negative regulatory effect upon its own transport.
K, Séron   +3 more
openaire   +2 more sources

Uracil restores susceptibility of methicillin-resistant Staphylococcus aureus to aminoglycosides through metabolic reprogramming

open access: yesFrontiers in Pharmacology, 2023
Background: Methicillin-resistant Staphylococcus aureus (MRSA) has now become a major nosocomial pathogen bacteria and resistant to many antibiotics. Therefore, Development of novel approaches to combat the disease is especially important.
Lvyuan Fan   +8 more
doaj   +1 more source

Monotriazoles Derived from Uracil and Thymine as Corrosion Inhibitor for API 5L X52 Steel in 1 M H2SO4

open access: yesInternational Journal of Electrochemical Science, 2018
In this study, the corrosion inhibition of monotriazoles derived from uracil and thymine was studied with electrochemical impedance spectroscopy (EIS) on API 5L X52 steel in 1 M H2SO4.
A. Espinoza-Vázquez   +4 more
doaj   +1 more source

The role of Duschinsky rotation in intersystem crossing: A case study of uracil [PDF]

open access: yesJournal of the Serbian Chemical Society, 2011
The intersystem crossing rate for the transition between the lowest excited singlet and triplet electronic states of uracil was studied by means of ab initio methods.
Etinski Mihajlo
doaj   +1 more source

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