Baseline Dual-Energy Computed Tomography Urate Volume Predicts Fulfillment of Gout Remission After Two Years of Urate-Lowering Therapy. [PDF]
Arthritis Care Res (Hoboken)OBJECTIVE: This study aimed to identify variables that predict gout remission in people with erosive gout receiving urate-lowering therapy. METHODS: We analysed data from a 2-year, double-blind randomized-controlled trial of people with erosive gout ...
Tabi-Amponsah AD +10 more
europepmc +2 more sources
The impact of urate-lowering therapy on kidney function (IMPULsKF)
Počki, 2017 The concept of trial launched in Ukraine in 2017 with POEM design and 36-months duration is presented. It aims to investigate the impact of two target levels of urate-lowering therapy caused by hyperuricemia on kidney function and chronic kidney disease (CKD) progression measured by estimated glomerular filtration rate and albuminuria in 180 patients ...
D.D. Ivanov
openaire +3 more sources
Pacific community's perceptions on how to improve uptake of urate-lowering therapy for Pacific gout patients. [PDF]
Int J Equity HealthObjectivesThis study aims to explore the views of Pacific people on how to improve the management of urate-lowering therapy among Pacific gout patients in South Auckland.MethodsThe study used the Fa'afaletui model to explore the views on gout management ...
Ofanoa S +5 more
europepmc +2 more sources
Is Urate-lowering therapy a prevention of first gout episode? [PDF]
Quality in SportThe growing problem of gout is beginning to raise questions about how we can effectively prevent this disease. This work examines the effect of urate-lowering therapy on preventing the onset of a first episode of gout—an effect that is not entirely clear, despite the fact that such therapy is an essential tool for controlling gout flares.
Michał Szczepański +9 more
openaire +3 more sources
Urate lowering therapy in patients starting hemodialysis limit gout flares occurrence: ten years retrospective study [PDF]
BMC NephrologyBackground Uncontrolled gout can cause articular impairment but is also associated with a global and cardiovascular excess mortality, especially in dialysis population.
Alexia Steelandt +7 more
doaj +2 more sources
Treat-to-target urate-lowering therapy and hospitalizations for gout: results from a nationwide cohort study in England. [PDF]
Rheumatology, 2023 Mark D Russell, Abdel Douiri
exaly +2 more sources
Adherence with urate-lowering therapies for the treatment of gout [PDF]
Arthritis Research & Therapy, 2009 Abstract Introduction Adherence to urate-lowering drugs (ULDs) has not been well evaluated among those with gout. Our aim was to assess the level and determinants of non-adherence with ULDs prescribed for gout.
Harrold, Leslie R +6 more
openaire +3 more sources
Lowering Serum Urate With Urate‐Lowering Therapy to Target and Incident Fracture Among People With Gout [PDF]
, 2023 ObjectiveGout is associated with a higher risk of fracture; however, findings on the associations of hyperuricemia and urate-lowering therapy (ULT) with the risk of fracture have been inconsistent.
Houchen Lyu +17 more
core +1 more source
Rational use of recommendations for urate-lowering therapy: clinical examples [PDF]
, 2022 The results of gout therapy in many patients remain unsatisfactory, despite the availability of drugs and recommendations for its treatment. In addition to poor adherence to treatment by patients, medical errors and other reasons influence this situation.
O. V. Zhelyabina, M. S. Eliseev
core +1 more source
The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]
, 2009 Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
Allan Struthers +3 more
core +1 more source