Results 21 to 30 of about 2,566,374 (138)

Perceptions About Asymptomatic Hyperuricemia and Views About Urate-Lowering Therapy in People With Asymptomatic Hyperuricemia. [PDF]

open access: yesArthritis Care Res (Hoboken)
BACKGROUND/AIMS: Asymptomatic hyperuricemia is a precursor of gout and is also associated with cardiovascular disease and chronic kidney disease. The aim of this study was to understand perceptions about asymptomatic hyperuricemia and views about urate ...
Dalbeth N   +19 more
europepmc   +2 more sources

The many faces of gout: modern treatment concepts

open access: yesКлинический разбор в общей медицине, 2021
Gout is a systemic disease caused by the deposition of monosodium urate crystals in various tissues and organs with the subsequent development of autoinflammation.
Irina N. Bobkova, Elena S. Kamyshova
doaj   +1 more source

Lowering Serum Urate With Urate‐Lowering Therapy to Target and Incident Fracture Among People With Gout [PDF]

open access: yes, 2023
ObjectiveGout is associated with a higher risk of fracture; however, findings on the associations of hyperuricemia and urate-lowering therapy (ULT) with the risk of fracture have been inconsistent.
Houchen Lyu   +17 more
core   +1 more source

The Effect of Decrease in Serum Urate for the Risk of Gout Flares During Urate-Lowering Therapy Initiation Among Chinese Male Gout Patients: A Prospective Cohort Study. [PDF]

open access: yesJ Inflamm Res, 2023
Lei Pang,1– 4,* Xiaomei Xue,1– 4,* Yuwei He,1– 4 Can Wang,1– 4 Lin Han,1– 4 Maichao Li,1– 4 Han Qi,1– 4 Changgui Li,1– 4 Jie Lu1– 4 1Shandong Provincial Clinical Research Center for Immune Diseases and Gout, the Affiliated Hospital of Qingdao ...
Pang L   +8 more
europepmc   +2 more sources

Rational use of recommendations for urate-lowering therapy: clinical examples [PDF]

open access: yes, 2022
The results of gout therapy in many patients remain unsatisfactory, despite the availability of drugs and recommendations for its treatment. In addition to poor adherence to treatment by patients, medical errors and other reasons influence this situation.
O. V. Zhelyabina, M. S. Eliseev
core   +1 more source

The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]

open access: yes, 2009
Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
Allan Struthers   +3 more
core   +1 more source

SLC2A9 is a high-capacity urate transporter in humans [PDF]

open access: yes, 2008
Background Serum uric acid levels in humans are influenced by diet, cellular breakdown, and renal elimination, and correlate with blood pressure, metabolic syndrome, diabetes, gout, and cardiovascular disease. Recent genome-wide association scans have
Doblado M   +240 more
core   +1 more source

Urate-lowering therapy for heart failure

open access: yesСовременная ревматология, 2019
Heart failure (HF) is one of the major public health problems in developed countries. Hyperuricemia (HU) is often found in patients with chronic HF (CHF) and is a well-known independent predictor for mortality and re-hospitalization for the progression ...
O. V. Zhelyabina, M. S. Eliseev
doaj   +1 more source

Modulation of genetic associations with serum urate levels by body-mass-index in humans [PDF]

open access: yes, 2015
We tested for interactions between body mass index (BMI) and common genetic variants affecting serum urate levels, genome-wide, in up to 42569 participants.
Döring, Angela   +999 more
core   +3 more sources

Probabilistic sensitivity analysis for urate lowering therapy combined with naproxen.

open access: yes, 2022
Probabilistic sensitivity analysis for urate lowering therapy combined with naproxen.
Carly A. Janssen (12015373)   +5 more
core   +1 more source

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