Results 31 to 40 of about 2,554,026 (187)

Baseline Dual-Energy Computed Tomography Urate Volume Predicts Fulfillment of Gout Remission After Two Years of Urate-Lowering Therapy. [PDF]

open access: yesArthritis Care Res (Hoboken)
OBJECTIVE: This study aimed to identify variables that predict gout remission in people with erosive gout receiving urate-lowering therapy. METHODS: We analysed data from a 2-year, double-blind randomized-controlled trial of people with erosive gout ...
Tabi-Amponsah AD   +10 more
europepmc   +2 more sources

The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]

open access: yes, 2009
Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
Allan Struthers   +3 more
core   +1 more source

SLC2A9 is a high-capacity urate transporter in humans [PDF]

open access: yes, 2008
Background Serum uric acid levels in humans are influenced by diet, cellular breakdown, and renal elimination, and correlate with blood pressure, metabolic syndrome, diabetes, gout, and cardiovascular disease. Recent genome-wide association scans have
Doblado M   +240 more
core   +1 more source

Modulation of genetic associations with serum urate levels by body-mass-index in humans [PDF]

open access: yes, 2015
We tested for interactions between body mass index (BMI) and common genetic variants affecting serum urate levels, genome-wide, in up to 42569 participants.
Döring, Angela   +999 more
core   +3 more sources

Probabilistic sensitivity analysis for urate lowering therapy combined with naproxen.

open access: yes, 2022
Probabilistic sensitivity analysis for urate lowering therapy combined with naproxen.
Carly A. Janssen (12015373)   +5 more
core   +1 more source

Estradiol regulates intestinal ABCG2 to promote urate excretion via the PI3K/Akt pathway

open access: yesNutrition & Metabolism, 2021
Objectives The study of sex differences in hyperuricemia can provide not only a theoretical basis for this clinical phenomenon but also new therapeutic targets for urate-lowering therapy.
Lei Liu   +5 more
doaj   +1 more source

Cardiac and renal protective effects of urate-lowering therapy [PDF]

open access: yesRheumatology, 2017
Patients with gout often have co-morbidities such as cardiovascular disease, renal failure and metabolic syndrome components. Some studies, but not all, have suggested that hyperuricaemia and gout are associated with increased risk of myocardial infarction, renal failure and death primarily because of increased risk of cardiovascular events. Therefore,
Pascal, Richette   +2 more
openaire   +2 more sources

Contentious Issues in Gout Management: The Story so Far

open access: yesOpen Access Rheumatology: Research and Reviews, 2021
Mohamed Talaat,1 Kyle Park,1 Naomi Schlesinger2 1Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA; 2Division of Rheumatology, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 08903-0019 ...
Talaat M, Park K, Schlesinger N
doaj  

Experience with canakinumab in a patient with gout and IgA nephropathy

open access: yesСовременная ревматология, 2019
The paper discusses the results of clinically using the interleukin-1_ inhibitor canakinumab in a patient with chronic tophaceous gout, IgA nephropathy, and chronic kidney disease with resistance to traditional anti-inflammatory drugs (colchicine ...
E. V. Ilyinykh, M. S. Eliseev
doaj   +1 more source

Pacific community's perceptions on how to improve uptake of urate-lowering therapy for Pacific gout patients. [PDF]

open access: yesInt J Equity Health
ObjectivesThis study aims to explore the views of Pacific people on how to improve the management of urate-lowering therapy among Pacific gout patients in South Auckland.MethodsThe study used the Fa'afaletui model to explore the views on gout management ...
Ofanoa S   +5 more
europepmc   +2 more sources

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