Results 31 to 40 of about 3,397 (111)

Biobanked Liver Organoids: A Roadmap for Precision Hepatology

BioEssays, Volume 48, Issue 6, June 2026.
Cryopreservation‐enabled biobanking transforms archived human liver tissue into standardized, quality‐controlled organoid resources. By decoupling organoid generation from the availability of fresh tissue, this infrastructure enables scalable, reproducible, and clinically actionable liver models that support precision hepatology, drug development, and ...
Elisa J. Cabré, Silvia Cobo‐González, Luis Sánchez Valle, Sonia Martínez, María Del Pilar Ramos‐Álvarez, Yanira Sáez‐Álvarez   +5 more
wiley   +1 more source

Pharmacological inhibition of receptor protein tyrosine phosphatase β/ζ decreases Aβ plaques and neuroinflammation in the hippocampus of APP/PS1 mice

Frontiers in Pharmacology
Alzheimer’s disease (AD) is a major neurodegenerative disorder that courses with chronic neuroinflammation. Pleiotrophin (PTN) is an endogenous inhibitor of Receptor Protein Tyrosine Phosphatase (RPTP) β/ζ which is upregulated in different ...
Teresa Fontán-Baselga, Héctor Cañeque-Rufo, Héctor Cañeque-Rufo, Elisa Rivera-Illades, Esther Gramage, José María Zapico, Beatriz de Pascual-Teresa, María Del Pilar Ramos-Álvarez, Gonzalo Herradón, Marta Vicente-Rodríguez   +9 more
doaj   +1 more source

N-Ribosyltransferase From Archaeoglobus veneficus: A Novel Halotolerant and Thermostable Biocatalyst for the Synthesis of Purine Ribonucleoside Analogs

Frontiers in Bioengineering and Biotechnology, 2020
Nucleoside-2′-deoxyribosyl-transferases (NDTs) catalyze a transglycosylation reaction consisting of the exchange of the 2′-deoxyribose moiety between a purine and/or pyrimidine nucleoside and a purine and/or pyrimidine base.
Javier Acosta, Jon Del Arco, Victor Pisabarro, Federico Gago, Jesús Fernández-Lucas, Jesús Fernández-Lucas   +5 more
doaj   +1 more source

Implication of the PTN/RPTPβ/ζ Signaling Pathway in Acute Ethanol Neuroinflammation in Both Sexes: A Comparative Study with LPS

Biomedicines, 2023
Binge drinking during adolescence increases the risk of alcohol use disorder, possibly by involving alterations of neuroimmune responses. Pleiotrophin (PTN) is a cytokine that inhibits Receptor Protein Tyrosine Phosphatase (RPTP) β/ζ.
María Rodríguez-Zapata, Milagros Galán-Llario, Héctor Cañeque-Rufo, Julio Sevillano, María Gracia Sánchez-Alonso, José M. Zapico, Marcel Ferrer-Alcón, María Uribarri, Beatriz de Pascual-Teresa, María del Pilar Ramos-Álvarez, Gonzalo Herradón, Carmen Pérez-García, Esther Gramage   +12 more
doaj   +1 more source

Multidimensional Poverty and Deprivation in Informal Settlements: A Gendered Perspective From the South African Multidimensional Poverty Index

Poverty &Public Policy, Volume 18, Issue 2, June 2026.
ABSTRACT Rapid urbanisation and persistent socio‐economic inequality continue to entrench multidimensional poverty within South Africa's urban informal settlements, with women and female‐headed households experiencing disproportionate deprivation. This study analysed primary household survey data collected in 2023 from 322 households across three ...
Adrino Mazenda, Stellah Lubinga, Hayley Boks, Moses Lubinga   +3 more
wiley   +1 more source

Prevalence of vitamin D status and its association with overweight or obesity in a population of Colombian children and adolescents

Journal of Nutritional Science, 2020
The present study aimed to estimate the prevalence of 25-OH-D status (insufficiency and deficiency) in children and adolescents residing in Bucaramanga, Colombia and to determine its association with excess weight.
Lyda Z. Rojas, Doris C. Quintero-Lesmes, Edna M. Gamboa-Delgado, Elizabeth Guio, Norma C. Serrano   +4 more
doaj   +1 more source

Contribution of allergy in the acquisition of uncontrolled severe asthma

Frontiers in Medicine, 2022
Asthma is a multifactorial, heterogeneous disease that has a challenging management. It can be divided in non-allergic and allergic (usually associated with house dust mites (HDM) sensitization).
María Isabel Delgado Dolset, David Obeso, David Obeso, Juan Rodriguez-Coira, Juan Rodriguez-Coira, Alma Villaseñor, Alma Villaseñor, Heleia González Cuervo, Ana Arjona, Coral Barbas, Domingo Barber, Teresa Carrillo, Teresa Carrillo, María M. Escribese, María M. Escribese   +14 more
doaj   +1 more source

From pollen provision to pollinator: Species‐specific sterol assimilation by wild bees in urban landscapes

Functional Ecology, Volume 40, Issue 6, Page 1906-1920, June 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Human‐driven landscape change, particularly urbanization, is reshaping pollinator communities, yet the functional traits that mediate species persistence remain poorly understood. Dietary specialization is commonly used to predict species vulnerability.
Yan Yang, Joan Casanelles‐Abella, Marco Moretti, Consuelo M. De Moraes, Mark C. Mescher, Pengjuan Zu   +5 more
wiley   +1 more source

Environmental governance in the face of collapse: The case of Acapulco, Mexico, between tourist splendour and ecological risk

Ecological Solutions and Evidence, Volume 7, Issue 2, April–June 2026.
Underwater clean‐up efforts in Acapulco Bay reveal the visible consequences of chronic coastal pollution. This study shows how Environmental Risk Assessments (ERAs) can integrate scientific evidence, regulatory frameworks and practitioner experience to identify pollution sources and guide more effective coastal governance in cities of the Global South.
Sinuhé Hernández Márquez, María Eugenia Zamudio‐Resendiz, María Luisa Núñez Resendiz, Montserrat Murrieta Alarcón, Alejandro Federico Alva Martínez, Laura Margarita Márquez Valdelamar, Nelly María López Ortiz, Carlos Alberto Sandoval Navarrete, Alberto Pérez Rojas, Alma Socorro Sobrino Figueroa, Yanin Islas Barrios, Ricardo Caballero Fuentes, Nataly Graciela Santos Bustos, Abel Sentíes   +13 more
wiley   +1 more source

Effects of Manual Therapy and Strengthening Exercise on Pain in Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Applied Sciences
This systematic review and meta-analysis aimed to determine whether manual therapy (MT) and strengthening exercises (SE) reduce pain in patients with knee osteoarthritis (KO). Clinical trials were identified through a search of PubMed, PEDro, Scopus, and
Beatriz Serrano-García, Carmen Belén Martínez-Cepa, Francisco Forriol, Santiago Angulo-Díaz-Parreño, Juan Andrés Mesa-Jiménez, Juan Carlos Zuil-Escobar   +5 more
doaj   +1 more source