Results 21 to 30 of about 3,484 (108)

Proteasomal Degradation of Zn-Dependent Hdacs: The E3-Ligases Implicated and the Designed Protacs That Enable Degradation

Molecules, 2021
Protein degradation by the Ubiquitin-Proteasome System is one of the main mechanisms of the regulation of cellular proteostasis, and the E3 ligases are the key effectors for the protein recognition and degradation.
Laura Márquez-Cantudo, Ana Ramos, Claire Coderch, Beatriz de Pascual-Teresa   +3 more
doaj   +1 more source

Maternal Fructose Intake Induces Insulin Resistance and Oxidative Stress in Male, but Not Female, Offspring

Journal of Nutrition and Metabolism, 2015
Objective. Fructose intake from added sugars correlates with the epidemic rise in metabolic syndrome and cardiovascular diseases. However, consumption of beverages containing fructose is allowed during gestation.
Lourdes Rodríguez, Paola Otero, María I. Panadero, Silvia Rodrigo, Juan J. Álvarez-Millán, Carlos Bocos   +5 more
doaj   +1 more source

Digestibilidad aparente de materia seca, proteína y carbohidratos de la dieta con ensilado biológico de harina de maíz en Cryphiops (C.) caementarius

Revista Peruana de Biología, 2022
El objetivo del estudio fue determinar la digestibilidad aparente de la materia seca, proteína y carbohidratos de la dieta con ensilado biológico de harina de maíz en Cryphiops (C.) caementarius.
Jean Baltodano Tapia, Erick Olivares Narcizo, Walter Reyes Avalos   +2 more
doaj   +1 more source

Metabolomics and biochemical alterations caused by pleiotrophin in the 6-hydroxydopamine mouse model of Parkinson’s disease

Scientific Reports, 2022
Pleiotrophin (PTN) is a cytokine involved in nerve tissue repair processes, neuroinflammation and neuronal survival. PTN expression levels are upregulated in the nigrostriatal pathway of Parkinson’s Disease (PD) patients.
Esther Gramage, Jorge Sáiz, Rosalía Fernández-Calle, Yasmina B. Martín, María Uribarri, Marcel Ferrer-Alcón, Coral Barbas, Gonzalo Herradón   +7 more
doaj   +1 more source

Molecular Imaging Probes Based on Matrix Metalloproteinase Inhibitors (MMPIs)

Molecules, 2019
Matrix metalloproteinases (MMPs) are a family of zinc- and calcium-dependent endopeptidases which are secreted or anchored in the cell membrane and are capable of degrading the multiple components of the extracellular matrix (ECM).
Loganathan Rangasamy, Bruno Di Geronimo, Irene Ortín, Claire Coderch, José María Zapico, Ana Ramos, Beatriz de Pascual-Teresa   +6 more
doaj   +1 more source

Epidemiology of Wildlife Infectious Diseases

Veterinary Sciences, 2023
The rise of infectious diseases in wildlife has become a severe concern recently, not only in relation to wildlife preservation but also for human health [...]
Angela Magnet, Fernando Izquierdo
doaj   +1 more source

New Advances in the Exploration of Esterases with PET and Fluorescent Probes

Molecules, 2023
Esterases are hydrolases that catalyze the hydrolysis of esters into the corresponding acids and alcohols. The development of fluorescent probes for detecting esterases is of great importance due to their wide spectrum of biological and industrial ...
Alba Gil-Rivas, Beatriz de Pascual-Teresa, Irene Ortín, Ana Ramos   +3 more
doaj   +1 more source

Use of Two PGPB Strains for the Valorization of Wastewater Sludge and Formulation of a Biofertilizer for the Recovery of Quercus ilex

Life
In response to the growing demand for agricultural production and the need for more sustainable practices, the use of biofertilizers based on the valorization of agricultural residues is presented as an alternative to traditional chemical fertilizers ...
Vanesa M. Fernández-Pastrana, Daniel González-Reguero, Marina Robas-Mora, Diana Penalba-Iglesias, María José Pozuelo de Felipe, Agustín Probanza, Pedro Jiménez-Gómez   +6 more
doaj   +1 more source

Tagatose consumption provokes metabolic syndrome features in rat males from mothers that consumed fructose during their pregnancy

Molecular Medicine
Background Maternal fructose intake induces harmful effects in progeny. However, this sugar is not contraindicated during pregnancy. On the other hand, the use of low-calorie sweeteners, such as tagatose, is increasing.
Elena Fauste, Madelín Pérez-Armas, Cristina Donis, Paola Otero, Mª Isabel Panadero, Carlos Bocos   +5 more
doaj   +1 more source

From Crisis to Resilience: Rethinking Urban Flooding and Groundwater Recharge in Bengaluru City, India

World Water Policy, Volume 12, Issue 3, August 2026.
ABSTRACT Bengaluru, a primary metropolitan centre in India, is currently grappling with the dual crises of urban flooding and severe groundwater depletion. These challenges are driven by rapid urbanization, which has seen built‐up areas increase from 42% to 86% over two decades, resulting in a dramatic loss of vegetation and wetlands.
S. Biswas, S. V. B. Patel, B. Maheshwari
wiley   +1 more source