Results 211 to 220 of about 2,310,068 (246)

APE1 promotes lung adenocarcinoma through G4-mediated transcriptional reprogramming of urea cycle metabolism. [PDF]

iScience
Yu Y, Cen C, Shao Z, Wang C, Wang Y, Miao Z, Sun M, Wang C, Xu Q, Liang K, Zhou J, Zhou D, Ji H, Xu G, Du Y.   +14 more
europepmc   +1 more source

Fire‐Safe Hierarchical Solid Polymer Electrolytes Enabled by Dual‐Functional Microcapsules for Lithium Metal Batteries

Advanced Science, EarlyView.
Dual‐functional fire‐safe microcapsules are integrated into hierarchical solid polymer electrolytes to provide sequential protection against thermal abuse. The ammonium hydrogen phytate‐modified shell forms a protective char barrier, while the thermally triggered release of perfluoro(2‐methyl‐3‐pentanone) actively suppresses combustion, enabling safer ...
Ziqi Huang, Jiuqing Gui, Qiaoying Cao, Yong Xiao, Hang Hu, Yeru Liang   +5 more
wiley   +1 more source

Amino Acid Metabolism and Immune Dysfunction in Urea Cycle Disorders: T and B Cell Perspectives. [PDF]

J Inherit Metab Dis
Gemici Karaaslan B, Kiykim A, Burtecene N, Gokden M, Cansever MS, Hopurcuoglu D, Cengiz GN, Topcu B, Zubarioğlu T, Kiykim E, Cokuğras H, Aktuglu Zeybek AC.   +11 more
europepmc   +1 more source

Context‐Dependent Inverse Association of Glucose–Lipid Metabolic Status With Anemia: Evidence From Multinational Multicohort Analyses

Advanced Science, EarlyView.
Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang, Xinxing Wang, Lianfeng Xie, Wenna Ding, Yingyong Yin, Mei Yao, Zhibo Cui, Kaiqiang Tang, Lijie Zhong, Zhi Wang, Jia Wang, Lei Lei, Xiaoxiao Qu, Chi‐E. Qiu   +13 more
wiley   +1 more source

Global research dynamics in urea cycle disorders: a bibliometric study highlighting key players and future directions. [PDF]

Orphanet J Rare Dis
Wang Y, Wang X, Zhang H, Zhu B.
europepmc   +1 more source

Dual Randomness From Spatial and Temporal Variations in Stochastic Zinc Gallate Nanoclusters for PUF and TRNG Co‐Driven Image Generation

Advanced Science, EarlyView.
A dual‐randomness hardware platform is demonstrated by integrating PUF and TRNG functionalities into mixed‐ZGO nanoclusters. By leveraging spatial and temporal stochasticity, the mixed‐ZGO NCs device enables both unique identification and random signal generation.
Seungme Kang, Wangmyung Choi, Jueun Lee, Yeong Kwon Kim, Byung Chul Jang, Wonjun Shin, Hocheon Yoo   +6 more
wiley   +1 more source

Hyperammonaemic encephalopathy due to non-functioning urea cycle as a complication to gastric bypass surgery. [PDF]

Metab Brain Dis
Kjærgaard K, Eriksen PL, Nøhr TK, Pedersen SB, Gravholt CH, Vilstrup H, Thomsen KL.   +6 more
europepmc   +1 more source

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

Advanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian, Guicheng Zhao, Xiang Wang, Xinyao Tang, Gan Shen, Tiechao Ruan, Chuan Jiang, Shikun Zhao, Jincheng Zhang, Xinyue Cui, Liangchai Zhuo, Jun Ma, Yihong Yang, Tingting Lin, Ying Shen   +14 more
wiley   +1 more source

Urea cycle defects in adulthood: clinical presentation, diagnosis and treatment in genetically encoded hepatic metabolic disorders with a potential for encephalopathy. [PDF]

Metab Brain Dis
Das AM.
europepmc   +1 more source

PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7‐dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma

Advanced Science, EarlyView.
PLOD1 interacts with ENO1 and limits its FBXW7‐dependent ubiquitination and proteasomal degradation through a mechanism requiring PLOD1 catalytic activity. ENO1 stabilization sustains glycolysis, promoting glioblastoma cell proliferation, migration, and temozolomide resistance.
Fen Xue, Dingkong Liang, Xin Chen, Fei Fan, Xiayun He   +4 more
wiley   +1 more source