Results 81 to 90 of about 2,310,068 (246)

Beyond Presumptions: Toward Mechanistic Clarity in Metal‐Free Carbon Catalysts for Electrochemical H2O2 Production via Data Science

open access: yesAdvanced Materials, EarlyView.
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu   +3 more
wiley   +1 more source

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

open access: yesAdvanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen   +8 more
wiley   +1 more source

Strong Fully Reprocessable Engineered Wood Composites

open access: yesAdvanced Materials, EarlyView.
Engineering a hyperbranched adhesive with complementary imine‐bond and hydrogen‐bond networks, combining it with wood particles to fabricate the wood composite (WP/HTP) under mild hot‐pressing conditions. The WP/HTP exhibits 100% mechanical strength recovery after three cycles of reprocessing, and the reprocessed modulus of rupture (MOR) and modulus of
Xilin Zhang   +9 more
wiley   +1 more source

Hepatitis C Virus Dysregulates Polyamine and Proline Metabolism and Perturbs the Urea Cycle

open access: yesCells
Hepatitis C virus (HCV) is an oncogenic virus that causes chronic liver disease in more than 80% of patients. During the last decade, efficient direct-acting antivirals were introduced into clinical practice.
Natalia F. Zakirova   +17 more
doaj   +1 more source

Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells

open access: yesMolecular Therapy: Nucleic Acids, 2016
Urea cycle disorders are incurable enzymopathies that affect nitrogen metabolism and typically lead to hyperammonemia. Arginase deficiency results from a mutation in Arg1, the enzyme regulating the final step of ureagenesis and typically results in ...
Patrick C Lee   +14 more
doaj   +1 more source

Glutamine synthetase limits β-catenin–mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1

open access: yesThe Journal of Clinical Investigation, 2022
Glutamine synthetase (GS) catalyzes de novo synthesis of glutamine that facilitates cancer cell growth. In the liver, GS functions next to the urea cycle to remove ammonia waste.
Weiwei Dai   +16 more
doaj   +1 more source

Phase‐Engineered MoS2 Quantum Monolayer Catalysts

open access: yesAdvanced Materials, EarlyView.
A new type of catalyst model—phase‐engineered MoS2 quantum‐monolayer catalyst (∼0.8 nm thick, < 6 nm in the lateral size; switchable freely among metallic 1T, semiconducting 2H, and a hybrid phase of metallic‐semiconducting 1T‐2H)—is reported. It can efficiently and stably drive photochemical H2, syngas and ammonia synthesis as a catalyst or co ...
Ruijie Yang   +12 more
wiley   +1 more source

Ionic Cocrystal Programming of Spatial Ionic Organization in Carbon Nitrides Enables Highly Efficient H2O2 Photosynthesis

open access: yesAdvanced Materials, EarlyView.
Ionic cocrystal‐programmed ionic organization establishes a general strategy for electrostatic programming in polymeric photocatalysts. ABSTRACT Controlling the spatial organization of ions in polymeric photocatalysts remains a fundamental challenge for optimizing charge transport and catalytic selectivity in solar‐driven hydrogen peroxide (H2O2 ...
Anna Lo Presti   +6 more
wiley   +1 more source

Activities of Urea Cycle Enzymes in Tumor-Bearing Mice [PDF]

open access: yes
1971-03The hepatic arginase activity was found to be elevated significantly in tumorbearing mice at the terminal stage. Furthermore, other enzymes in the urea cycle, ornithine transcarbamylase, arginine synthetase (over all reaction) and ...
SANO, MINEO, 49555
core   +2 more sources

Pulsed Oxidative–Reductive Electrolysis Over Dual Cu and Co Single‐Atom Sites for Urea Electrosynthesis

open access: yesAdvanced Materials, EarlyView.
Alternating oxidative–reductive pulses synchronize CO2‐derived *CO and NH3‐derived *NHx intermediates over dual Cu and Co single‐atom sites, enabling urea and ethyl urea formation with a total C─N Faradaic efficiency of 42 ± 4%. In situ spectroscopy and theoretical calculations elucidate complementary Cu and Co functions, while oxidative controls ...
Putri Ramadhany   +8 more
wiley   +1 more source

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