Results 21 to 30 of about 38,777 (249)
Aging increases UT‐B urea transporter protein abundance in brains of male mice [PDF]
Physiological ReportsFacilitative UT‐B urea transporters in the brain play an important role in regulating levels of urea in various cell types, including astrocytes. Numerous studies have reported increased UT‐B RNA expression with aging and in neurological disorders, such ...
Farhana Pinki +3 more
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Scientific Reports, 2023 The milk urea concentration (MUC) serves as indicator of urinary nitrogen emissions, but at comparable crude protein (CP) intake, cows with high (HMU) and low (LMU) MUC excrete equal urea amounts.
Marie C. Prahl +3 more
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Preclinical Pharmacokinetic Studies of a Novel Diuretic Inhibiting Urea Transporters
Molecules, 2022 Urea transporter (UT) inhibitors are a class of promising novel diuretics that do not cause the imbalance of Na+, K+, Cl−, and other electrolytes. In our previous studies, 25a, a promising diuretic candidate inhibiting UT, was discovered and showed ...
Yue Xu +6 more
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Fluorinated tetrapodal anion transporters
iScience, 2023 Summary: Synthetic anion transporters show potential in treating life-threatening diseases like cystic fibrosis and cancer. However, with increasingly complex transporter architectures designed to control anion binding and transport, it is important to ...
Alexander M. Gilchrist +4 more
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Structure of Urea Transporters [PDF]
, 2014 Members of the urea transporter (UT) family mediate rapid, selective transport of urea down its concentration gradient. To date, crystal structures of two evolutionarily distant UTs have been solved. These structures reveal a common UT fold involving two structurally homologous domains that encircle a continuous membrane-spanning pore and indicate that
Elena J, Levin, Ming, Zhou
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Humic acids induce the expression of nitrate transporters in passion-fruit seedlings [PDF]
Revista Brasileira de Fruticultura, 2023 The management of organic fertilization in passion fruit has been carried out empirically based on the responses of the crops and the experience of farmers.
Paulo Fernando Marques Cavalcanti Filho +4 more
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Frontiers in Microbiology, 2023 Ammonia-oxidizing archaea (AOA) and bacteria (AOB), nitrite-oxidizing bacteria (NOB), and complete ammonia oxidizers (comammox) are responsible for nitrification in nature; however, some groups have been reported to utilize labile-dissolved organic ...
Qian Liu +7 more
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Mammalian urea transporters [PDF]
Experimental Physiology, 2009 Urea transporters (UTs) encoded by the Slc14a1 (UT‐B) and Slc14a2 (UT‐A) genes mediate urea flux across cellular membranes. Considerable research has accrued detailing the function and distribution of members of both subfamilies. Much research effort has focused on the kidney, where UTs are highly expressed and function to promote urine concentration ...
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Screening of Urea Transporter Inhibitors in Celery Seeds by UPLC-TOF-MS
Medical Sciences Forum, 2022 Urea transporters (UTs) are a kind of transmembrane protein that specifically permeate urea, and play an important role in the mechanism of urine concentration.
Guanzhong Chen +4 more
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UT-B-deficient mice develop renal dysfunction and structural damage
BMC Nephrology, 2012 Background Urea transporter UT-B is the major urea transporter in erythrocytes and the descending vasa recta in the kidney. In this study, we investigated the effects of long-term UT-B deficiency on functional and structural defect in the kidney of 16 ...
Zhou Lei +6 more
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