Results 41 to 50 of about 25,978 (275)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Modelling urea cycle disorders using iPSCs

npj Regenerative Medicine, 2022
The urea cycle is a liver-based pathway enabling disposal of nitrogen waste. Urea cycle disorders (UCDs) are inherited metabolic diseases caused by deficiency of enzymes or transporters involved in the urea cycle and have a prevalence of 1:35,000 live ...
Claire Duff, Julien Baruteau
doaj   +1 more source

Urea transporters in the mammalian brain

, 2022
Facilitative urea transporters encoded by two distinct genes: SLC14A2 (UT-A) and SLC14A1 (UT-B) facilitate movement of urea across plasma cell membranes and have been found in different locations within different tissues in various mammalian species ...
Pinki, Farhana
core  

Machine Learning‐Supported Analysis for Predicting and Visualizing Nonlinear Relationships Between Material Properties in Electroplated Chromium Layers

Advanced Engineering Materials, EarlyView.
This study applies machine learning regression to predict chromium layer thickness in decorative trivalent chromium electroplating, using 441 experiments from laboratory‐scale (1L) and pilot‐scale (14L) setups. Tree‐based models, particularly CatBoost, outperformed linear regression by capturing nonlinear parameter interactions (R2$R^2$ up to 0.77 ...
Christoph Baumer, Christopher Mai, Luca Eisentraut, Andreas Bund, Ricardo Buettner   +4 more
wiley   +1 more source

Jugular arginine supplementation increases lactation performance and nitrogen utilization efficiency in lactating dairy cows

Journal of Animal Science and Biotechnology, 2019
Background Enhancing the post-ruminal supply of arginine (Arg), a semi-essential amino acid (AA), elicits positive effects on milk production. Our objective was to determine the effects of Arg infusion on milk production parameters and aspects of ...
Luoyang Ding, Yizhao Shen, Yifan Wang, Gang Zhou, Xin Zhang, Mengzhi Wang, Juan J. Loor, Lianmin Chen, Jun Zhang   +8 more
doaj   +1 more source

Structure, regulation and physiological roles of urea transporters

, 1996
Structure, regulation and physiological roles of urea transporters. Urea is the major constituent of the urine and the principal means for disposal of nitrogen derived from amino acid metabolism.
Smith, Craig P., You, Guofeng, Shayakul, Chairat, Lee, Wen-Sen, Hediger, Matthias A., Kanai, Yoshikatsu   +5 more
core   +1 more source

Liquid Phase Transmission Electron Microscopy: A Window into the Early Stages of Complex Material Formation

Advanced Functional Materials, EarlyView.
Liquid‐phase transmission electron microscopy enables direct observation of nucleation and growth processes in solution. This review is dedicated to the remembrance of Helmut Cölfen and highlights recent studies on complex materials—oxides, biominerals, organic–inorganic crystals—which were central to his research activity. It summarizes key milestones,
Charles Sidhoum, Vinavadini Ramnarain, Nathaly Ortiz Peña, Dris Ihiawakrim, Clément Sanchez, Ovidiu Ersen   +5 more
wiley   +1 more source

The Therapeutic Effect and the Potential Mechanism of Flavonoids and Phenolics of Moringa oleifera Lam. Leaves against Hyperuricemia Mice

Molecules, 2022
The aim of this study is to evaluate the anti-hyperuricemia effect and clarify the possible mechanisms of flavonoids and phenolics of MOL (MOL-FP) in mice.
Xiaowei Luo, Lipeng Zhou, Shukai Wang, Jing Yuan, Zihao Chang, Qian Hu, Yinxin Chen, Yuqi Liu, Ya Huang, Baojin Wang, Ye Gao, Zhaohui Wang, Yitong Cui, Yue Liu, Lanzhen Zhang   +14 more
doaj   +1 more source

Urea Movement Across Mouse Colonic Plasma Membranes Is Mediated by UT-A Urea Transporters

, 2004
Background & Aims: Urea is a major nitrogen source for commensal bacteria that inhabit the large intestine. UT-A urea transporters mediate urea movement across plasma membranes.
Smith, Craig P., Stewart, Gavin S., Thévenod, Frank, Fenton, Robert A.   +3 more
core   +1 more source

Polymer Interface Enables Reversible Quasi‐Solid Sulfur Conversion in Sodium‐Sulfur Batteries

Advanced Functional Materials, EarlyView.
The polymer interface enables a stable quasi‐solid sulfur conversion pathway in room‐temperature Na─S batteries. The coating regulates Na+ transport, stabilizes the cathode–electrolyte interphase, and accommodates mechanical stress, suppressing electrolyte decomposition and sulfur migration, thereby improving reaction uniformity, reducing polarization,
Reza Andaveh, Ying Zhao, Enzhong Jin, Zixin Zhang, Vinicius Martins, Parham Pirayesh, Yi Gan, Yi Yuan, Yijia Wang, Frederick Benjamin Holness, Changhong Cao, Jun Song, Yang Zhao   +12 more
wiley   +1 more source