ABSTRACT Background and Aim Although clarithromycin resistance is a major cause of empirical triple therapy failure for Helicobacter pylori eradication, the clinical relevance of amoxicillin susceptibility remains uncertain. We first compared eradication outcomes between empirical and susceptibility‐guided tailored triple therapy and then evaluated the
Hoyoung Wang +10 more
wiley +1 more source
Exploring the Synthetic Chemistry of Phenyl-3-(5-aryl-2-furyl)- 2-propen-1-ones as Urease Inhibitors: Mechanistic Approach through Urease Inhibition, Molecular Docking and Structure-Activity Relationship. [PDF]
Fatima M +10 more
europepmc +1 more source
Introduction. Mycobacterium tuberculosis urease (MTU), being an important factor of the bacterium viability and virulence, is an attractive target for anti-tuberculosis drugs acting by inhibition of urease activity.
Yu Lisnyak, A Martynov
doaj
Exploring Amantadine Derivatives as Urease Inhibitors: Molecular Docking and Structure-Activity Relationship (SAR) Studies. [PDF]
Ahmed A +10 more
europepmc +1 more source
Urease inhibitors: current advances, therapeutic potentials, and clinical challenges. [PDF]
Alzoubi OH +12 more
europepmc +1 more source
Novel benzimidazole derivatives; synthesis, bioactivity and molecular docking study as potent urease inhibitors. [PDF]
Saeedian Moghadam E +5 more
europepmc +1 more source
The development of new nitrogen fertilizers is necessary to optimize crop production whilst improving the environmental aspects arising from the use of nitrogenous fertilization as a cultural practice.
Cruchaga, Saioa +5 more
core +1 more source
Provenance-Associated Confounding in Cross-Collection Comparisons of Urease Inhibitors: A Quantified Reference Scale and a Domain-Aware Alternative. [PDF]
Farías-Abarca J +8 more
europepmc +1 more source
N-Aryl-3,4-dihydroisoquinoline Carbothioamide Analogues as Potential Urease Inhibitors. [PDF]
Ali F +9 more
europepmc +1 more source
Urease, a metalloenzyme that catalyzes urea hydrolysis, is associated with nitrogen losses in soils. In agricultural settings, although the commercial inhibitor N -(butyl)thiophosphoric triamide (NBPT) is widely used, its low stability under adverse ...
Modolo, Luzia Valentina +7 more
core +1 more source

