Results 181 to 190 of about 678,840 (238)

Novel benzimidazole-based azine derivatives as potent urease inhibitors: synthesis, <i>in vitro</i> and <i>in silico</i> approach. [PDF]

Future Med Chem
Hamidullah, Alam A, Elhenawy AA, Ali M, Latif A, Khan A, Al-Harrasi A, Ahmad M.   +7 more
europepmc   +1 more source

Complexes of N- and O-Donor Ligands as Potential Urease Inhibitors. [PDF]

ACS Omega, 2020
Shah SR, Shah Z, Khiat M, Khan A, Hill LR, Khan S, Hussain J, Csuk R, Anwar MU, Al-Harrasi A.   +9 more
europepmc   +1 more source

Rational design and <i>in vitro</i> testing of new urease inhibitors to prevent urinary catheter blockage. [PDF]

RSC Med Chem
Heylen RA, Cusick N, White T, Owen EJ, Patenall BL, Alm M, Thomsen P, Laabei M, Jenkins ATA.   +8 more
europepmc   +1 more source

Enzyme Inhibitory Kinetics and Molecular Docking Studies of Halo-Substituted Mixed Ester/Amide-Based Derivatives as Jack Bean Urease Inhibitors. [PDF]

Biomed Res Int, 2020
Rashid M, Rafique H, Roshan S, Shamas S, Iqbal Z, Ashraf Z, Abbas Q, Hassan M, Qureshi ZUR, Asad MHHB.   +9 more
europepmc   +1 more source

Unveiling Novel Urease Inhibitors for Helicobacter pylori: A Multi-Methodological Approach from Virtual Screening and ADME to Molecular Dynamics Simulations. [PDF]

Int J Mol Sci
Valenzuela-Hormazabal P, Sepúlveda RV, Alegría-Arcos M, Valdés-Muñoz E, Rojas-Pérez V, González-Bonet I, Suardíaz R, Galarza C, Morales N, Leddermann V, Castro RI, Benso B, Urra G, Hernández-Rodríguez EW, Bustos D.   +14 more
europepmc   +1 more source

Identification of novel bacterial urease inhibitors through molecular shape and structure based virtual screening approaches. [PDF]

RSC Adv, 2020
Imran M, Waqar S, Ogata K, Ahmed M, Noreen Z, Javed S, Bibi N, Bokhari H, Amjad A, Muddassar M.   +9 more
europepmc   +1 more source

Schiff bases and their metal complexes as urease inhibitors - A brief review. [PDF]

J Adv Res, 2018
de Fátima Â, Pereira CP, Olímpio CRSDG, de Freitas Oliveira BG, Franco LL, da Silva PHC.   +5 more
europepmc   +1 more source

In vitro biological evaluation and in silico studies of linear diarylheptanoids from Curcuma aromatica Salisb. as urease inhibitors. [PDF]

RSC Med Chem
Le TH, Ho DNP, Nguyen HX, Van Do TN, Nguyen MTT, Huynh LK, Nguyen NT.   +6 more
europepmc   +1 more source

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Rational Development of Bacterial Ureases Inhibitors

The Chemical Record, 2022
AbstractUrease, an enzyme that catalyzes the hydrolysis of urea, is a virulence factor of various pathogenic bacteria. In particular, Helicobacter pylori, that colonizes the digestive tract and Proteus spp., that can infect the urinary tract, are related to urease activity.
Saurabh Loharch, Łukasz Berlicki
openaire   +2 more sources

Applicability of Biosuppressin as an urease-inhibitor

International Urology and Nephrology, 1984
Prevention of the formation of struvite and carbonate-apatite calculi, which rapidly increase in size and tend to recur, is of prime importance. One of the urease inhibitors, hydroxycarbamide, was studied in vitro. The results are favourable and justify further studies aimed at the local application of the inhibitor.
A, Jávor, D, Frang, Z, Nagy
openaire   +2 more sources