Results 121 to 130 of about 52,663 (318)

Serum Proteomic and Metabolomic Signatures of High Versus Low Physical Function in Octogenarians

open access: yesAging Cell, Volume 24, Issue 5, May 2025.
Circulating factors are strongly implicated in modulating biological aging. In this study we show that the serum proteomic and metabolomic profile of high functioning octogenarians suggests lower activation of SASP, preservation of the tryptophan‐kynurenic pathway, higher lipophosphatidyl cholines promoting mitochondrial function, and reduced ...
Ceereena Ubaida‐Mohien   +11 more
wiley   +1 more source

Comparison of gabapentin and ketotifen in treatment of uremic pruritus in hemodialysis patients [PDF]

open access: yes, 2016
Objectives: Uremic pruritus is a common problem in hemodialysis patients. Several treatments have been used for decreasing itching in these patients. Gabapentin and ketotifen are two drugs used for treating uremic patients.The aim of this study was to ...
Amirkhanlou, S.   +4 more
core   +1 more source

Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial

open access: yesAging Cell, EarlyView.
Nicotinamide riboside improved arterial stiffness (cardio–ankle vascular index), reduced skin ulcer area, and showed a trend toward mitigating heel pad thinning in patients with Werner syndrome, with no serious adverse events. Metabolomic analysis revealed a significant decrease in creatinine, suggesting a potential suppression of renal functional ...
Mayumi Shoji   +15 more
wiley   +1 more source

Hemodynamic Studies in Chronic Uremia [PDF]

open access: bronze, 1969
Francesco Greco   +3 more
openalex   +1 more source

Epidemiology of diagnostic errors in pediatric emergency departments using electronic triggers

open access: yesAcademic Emergency Medicine, Volume 32, Issue 3, Page 226-245, March 2025.
Abstract Objectives We applied three electronic triggers to study frequency and contributory factors of missed opportunities for improving diagnosis (MOIDs) in pediatric emergency departments (EDs): return visits within 10 days resulting in admission (Trigger 1), care escalation within 24 h of ED presentation (Trigger 2), and death within 24 h of ED ...
Prashant Mahajan   +18 more
wiley   +1 more source

Increased Metabolic Rate in X-linked Hypophosphatemic Mice [PDF]

open access: yes, 1986
Hyp mice are a model for human X-linked hypophosphatemia, the most common form of vitamin D-resistant rickets. It has previously been observed that Hyp mice have a greater food consumption per gram body weight than do normal mice.
Meyer, M. H.   +2 more
core   +1 more source

Therapeutic efficacy of lanthanum carbonate combined with meglumine cyclophosphate on patients with uremia cardiomyopathy

open access: yesLinchuang shenzangbing zazhi, 2015
Objective To study the relationship of heart rate turbulence(HRT) in patients with uremia cardiomyopathy and investigate the curative effect and security of lanthanum carbonate combined with meglumine cyclophosphate(MAC) in patients with uremia ...
CHEN Xin   +3 more
doaj  

Defective ADP-Induced Platelet Factor 3 Activation in Uremia [PDF]

open access: bronze, 1967
Herbert I. Horowitz   +3 more
openalex   +1 more source

Endothelial damage and complement dysregulation in fetuses from pregnancies complicated by preeclampsia

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 5, Page 829-838, May 2025.
Preeclampsia fetuses show an altered profile of endothelial damage and complement biomarkers, like increased adhesion molecules, prothrombotic state, oxidative stress, and reduced complement membrane attack complex deposition on endothelial cells. Abstract Introduction Our objective was to evaluate the endothelial function profile and complement system
Alex Ramos   +17 more
wiley   +1 more source

Blood Coagulation in Uremic Patients Before and After Hemodialysis and Transplantation of the Kidney [PDF]

open access: yes, 1966
Marchioro, TL   +4 more
core   +1 more source

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