Results 191 to 200 of about 25,775 (238)

Uremic Toxin Receptor AhR Facilitates Renal Senescence and Fibrosis via Suppressing Mitochondrial Biogenesis. [PDF]

Adv Sci (Weinh)
Xie H, Yang N, Lu L, Sun X, Li J, Wang X, Guo H, Zhou L, Liu J, Wu H, Yu C, Zhang W, Lu L.   +12 more
europepmc   +1 more source

The uremic toxin indoxyl sulfate decreases osteocyte RANKL/OPG and increases Wnt inhibitor RNA expression that is reversed by PTH. [PDF]

JBMR Plus
Chen NX, O'Neill KD, Wilson HE, Srinivasan S, Bonewald L, Moe SM.   +5 more
europepmc   +1 more source

Resveratrol Mitigates Uremic Toxin-Induced Intestinal Barrier Dysfunction in Chronic Kidney Disease by Promoting Mitophagy and Inhibiting Apoptosis Pathways. [PDF]

Int J Med Sci
Zheng CM, Hou YC, Tsai KW, Hu WC, Yang HC, Liao MT, Lu KC.   +6 more
europepmc   +1 more source

Displacing the Burden: A Review of Protein-Bound Uremic Toxin Clearance Strategies in Chronic Kidney Disease. [PDF]

J Clin Med
Sánchez-Ospina D, Mas-Fontao S, Gracia-Iguacel C, Avello A, González de Rivera M, Mujika-Marticorena M, Gonzalez-Parra E.   +6 more
europepmc   +1 more source

Uremic toxin indoxyl sulfate induces trained immunity via the AhR-dependent arachidonic acid pathway in end-stage renal disease (ESRD). [PDF]

Elife
Kim HY, Kang YJ, Kim DH, Jang J, Lee SJ, Kim G, Koh HB, Ko YE, Shin HM, Lee H, Yoo TH, Lee WW.   +11 more
europepmc   +1 more source

Human gut-associated Bifidobacterium species salvage exogenous indole, a uremic toxin precursor, to synthesize indole-3-lactic acid via tryptophan. [PDF]

Gut Microbes
Yong CC, Sakurai T, Kaneko H, Horigome A, Mitsuyama E, Nakajima A, Katoh T, Sakanaka M, Abe T, Xiao JZ, Tanaka M, Odamaki T, Katayama T.   +12 more
europepmc   +1 more source

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Nondialyzable Uremic Toxins

Blood Purification, 2013
Nondialyzable uremic toxins can be defined as solutes producing adverse biological effects that consequently to peculiar physicochemical features (mainly their large size and hydrophobic character) cannot leave the blood stream through a dialysis membrane.
PIRODDI, MARTA, BARTOLINI, DESIREE, Ciffolilli S, GALLI, Francesco   +3 more
openaire   +2 more sources

Uremic toxins.

Kidney international. Supplement, 1988
It is the purpose of this paper to review our present knowledge about uremic toxicity, with a special emphasis on the methods that have been used to try to resolve this problem. More and more, sophisticated methods become available for the study of uremic toxicity.
Ringoir, S.M.G., Schoots, A.C., Vanholder, R.   +2 more
openaire   +2 more sources

An update on uremic toxins

International Urology and Nephrology, 2012
In the last decade, uremic toxicity as a potential cause for the excess of cardiovascular disease and mortality observed in chronic kidney disease gained more and more interest. This review focuses on uremic toxins with known cardiovascular effects and their removal. For protein-bound solutes, for example, indoxylsulfate and the conjugates of p-cresol,
N, Neirynck, R, Vanholder, E, Schepers, S, Eloot, A, Pletinck, G, Glorieux   +5 more
openaire   +2 more sources