Results 91 to 100 of about 116,102 (224)

CKD and uremic toxins

, 2021
All data from manuscript investigating kidney function after treatement to reduce protein bound uremic toxins in experimental ...
Ebba Sivertsson (11667481)
core   +1 more source

Illness in Children Presenting to the Emergency Department After International Travel: A 10‐Year Retrospective Analysis From the University Hospital of Helsinki, Finland

Acta Paediatrica, EarlyView.
ABSTRACT Aim We characterized infections after international travel and identified predictors of severe infection to refine management. Methods We conducted a retrospective cross‐sectional analysis of children aged 0–18 years presenting to Helsinki University Hospital Emergency Department within 90 days of international travel between January 1, 2015 ...
Tuula Pelkonen, Svetlana Vakkilainen
wiley   +1 more source

A Systematic Review of Uremic Toxin Concentrations and Cardiovascular Risk Markers in Pediatric Chronic Kidney Disease

Chronic kidney disease (CKD) can lead to cardiac dysfunction in a condition known as cardiorenal syndrome (CRS). It is postulated that the accumulation of uremic toxins in the bloodstream, as a consequence of declining kidney function, may contribute to ...
Aly Muhammad Salim, Steven C. Greenway, Heshini Dalpathadu, Andrew Wade   +3 more
core   +1 more source

Uremic Apelin and Leucocytic Angiotensin-Converting Enzyme 2 in CKD Patients

, 2020
Apelin peptides (APLN) serve as second substrates for angiotensin-converting enzyme 2 (ACE2) and, in contrast to angiotensin II (AngII), exert blood-pressure lowering and vasodilatation effects through binding to G-coupled APLN receptor (APLNR).
Christof Ulrich, Matthias Girndt, Bogusz Trojanowicz   +2 more
core   +1 more source

Association of Sarcopenia and Gut Microbiota Composition in Older Patients with Advanced Chronic Kidney Disease, Investigation of the Interactions with Uremic Toxins, Inflammation and Oxidative Stress

, 2021
Sarcopenia is a prevalent condition in chronic kidney disease (CKD). We determined gut microbiota (gMB) composition in CKD patients with or without sarcopenia. Furthermore, we investigated whether in these patients, there was any association between gMB,
Francesco Miragoli, Silvia Armelloni, Piergiorgio Messa, Francesca Zanoni, Maria Luisa Callegari, Elisabetta Margiotta, Simone Vettoretti, Lara Caldiroli, Vittoria Rizzo   +8 more
core   +1 more source

Non-dialyzable uremic toxins and renal tubular cell damage in CKD patients: a systems biology approach

European Journal of Medical Research
Background Chronic kidney disease presents global health challenges, with hemodialysis as a common treatment. However, non-dialyzable uremic toxins demand further investigation for new therapeutic approaches.
Roya Asadi, Pejman Shadpour, Akram Nakhaei   +2 more
doaj   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Contribution of Gut Microbiota-Derived Uremic Toxins to the Cardiovascular System Mineralization

, 2021
Chronic kidney disease (CKD) affects more than 10% of the world population and leads to excess morbidity and mortality (with cardiovascular disease as a leading cause of death).
Agata Winiarska, Iwona Filipska, Monika Knysak, Tomasz Stompór   +3 more
core   +1 more source

Uremic toxins and peritoneal dialysis

Kidney International, 2001
Uremic toxicity is related in part to the accumulation of toxic substances, the nature of which has only partly been characterized. Because of the use of a highly permeable membrane and better preservation of the residual renal function, it could be anticipated that some of these uremic toxins are more efficiently cleared across the peritoneal membrane,
Lameire, Norbert, Vanholder, Raymond, De Smet, Rita   +2 more
openaire   +2 more sources

Kidney Disease: A Multiorgan Perspective

Organ Medicine, EarlyView.
Muhammad Nauman Hashmi
wiley   +1 more source