Results 101 to 110 of about 116,102 (224)
Diabetic Medicine, EarlyView.Abstract Aims HNF1B variants cause autosomal dominant tubulointerstitial kidney disease (ADTKD‐HNF1B), but the phenotypic spectrum of variants of uncertain significance (VUS) remains incompletely defined. We aimed to characterise the multisystem phenotype associated with the HNF1B p.E105K variant and to examine the mechanism underlying insulin ...
YunZe Wang +5 more
wiley +1 more source
Hemodialysis International, EarlyView.ABSTRACT Background Uremic pruritus (UP) remains a common and distressing complication in patients with end‐stage renal disease (ESRD) receiving maintenance hemodialysis. The burden is particularly pronounced in low‐ and middle‐income countries where twice‐weekly hemodialysis is frequently practiced because of resource limitations. Gabapentin is widely
Bilal Mohsin +9 more
wiley +1 more source
Periodontitis and Rheumatoid Arthritis—Mechanistic Evidence
Journal of Periodontal Research, EarlyView.Periodontitis and rheumatoid arthritis are linked via the two‐hit model whereby early periodontal inflammation can lead to autoantibody production capable of interacting with inflamed synovial tissues. Subsequent systemic inflammation can exacerbate the periodontal inflammatory response and bacterial dysbiosis leading to further autoantibody production
Mark Bartold +2 more
wiley +1 more source
Relationship between vitamin D deficiency and early implant failure and osseointegration
Periodontology 2000, EarlyView.Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron +8 more
wiley +1 more source
, 2014 Chronic kidney disease (CKD) has been considered a major risk factor for cardiovascular diseases. Although great advances have recently been made in the pathophysiology and treatment of cardiovascular diseases, CKD remains a major global health problem ...
Shunsuke Ito, Masayuki Yoshida
core +1 more source
Impact of systemic diseases on periodontal remodeling: Mechanisms, mediators, and clinical relevance
Periodontology 2000, EarlyView.Abstract Background Periodontal remodeling is a continuous, adaptive process essential for maintaining the structural and functional integrity of periodontal tissues. While external factors such as bacterial biofilm, excessive forces, and poor oral hygiene are recognized triggers of periodontal pathologies, they do not fully explain their persistent ...
Michael Wolf +7 more
wiley +1 more source
Toxicity of Cytarabine Intravenous Constant Rate Infusion in Cats With Lymphoma
Veterinary and Comparative Oncology, EarlyView.ABSTRACT Cytarabine intravenous constant rate infusion (IV CRI) toxicity in cats with lymphoma has not been well documented. We aimed to assess toxicities following cytarabine IV CRI as a single‐agent or within a multiagent protocol in cats with lymphoma. Medical records of cats with lymphoma treated with cytarabine IV CRI, with documented dose, route,
Rachel Hanford +5 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu +4 more
wiley +1 more source
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials
Experimental Physiology, EarlyView.Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler +2 more
wiley +1 more source