Results 121 to 130 of about 27,152 (233)
ABSTRACT A 1‐year‐old female‐intact arctic fox (Vulpes lagopus) presented for diarrhea, lethargy, severe thrombocytopenia, and hyperbilirubinemia. Blood film evaluation revealed intracytoplasmic coccoid bacteria within moderate numbers of leukocytes consistent with infection by a rickettsial organism.
Jeremy P. Bessett +3 more
wiley +1 more source
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu +4 more
wiley +1 more source
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler +2 more
wiley +1 more source
Calcific uraemic arteriolopathy - A mini-review [PDF]
Calcific Uraemic Arteriolopathy (CUA) or calciphylaxis, is a thrombotic disorder of skin and subcutaneous tissue which typically presents with painful purpuric nodules that may progress to necrotic ulcers, and is a severe, life-threatening condition. CUA
Agapii, Rodica +7 more
core
Gut Microbiota‐Linked Benefits of Low‐Intensity Pulsed Ultrasound Rejuvenate the Ageing Muscle
ABSTRACT Background Ageing is an inevitable biological process that contributes to increased prevalence of age‐associated diseases, including sarcopenia, defined by progressive loss of muscle mass, functional decline and a heightened risk of injury. Developing effective interventions remains a critical clinical priority.
Jia‐Hua Jhuang +4 more
wiley +1 more source
Renal Disease Burden in Prurigo Nodularis: A Systematic Review and Meta‐Analysis
International Journal of Dermatology, EarlyView.
Natalia Chalupczak +3 more
wiley +1 more source
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source
Feet in Peril: Assessment of Feet in Patients Undergoing Haemodialysis
ABSTRACT Background Foot problems are common in haemodialysis patients, making treatment and disease management difficult due to their serious complications and creating a significant financial burden on healthcare expenses. Objective In this study, we assessed the foot problems in haemodialysis patients.
Aysun Ünal +4 more
wiley +1 more source
Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics
. ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically interact with host environments and self‐regulate their activity, offering superior adaptability, prolonged functionality, and ...
Shuifang Mao +3 more
wiley +1 more source
Effects of Renal and Hepatic Impairment on the Pharmacokinetics of Zilurgisertib
Aim Small‐molecule activin receptor‐like kinase‐2 inhibitor zilurgisertib (INCB000928) is under investigation in a pivotal trial for the treatment of fibrodysplasia ossificans progressiva (FOP), an ultrarare genetic condition. This analysis assessed effects of renal and hepatic impairment on zilurgisertib pharmacokinetics.
Yan‐ou Yang +5 more
wiley +1 more source

