Results 121 to 130 of about 116,102 (224)
Treatment with empagliflozin or dapagliflozin was associated with a modest increase in plasma concentration of TMAO in Type 2 diabetes patients. These findings suggest a possible class effect of SGLT‐2 inhibitors. Whether this effect impacts the overall clinical benefits of SGLT‐2 inhibitors needs to be subject to further investigation.
Katja B. Zimmer +6 more
wiley +1 more source
Emerging evidence supports the beneficial effects of dietary fiber supplementation in alleviating gut dysbiosis, which leads to a reduction in uremic toxins and inflammatory markers in chronic kidney disease (CKD) patients.
Wannasit Wathanavasin +3 more
core +1 more source
Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang +4 more
wiley +1 more source
To promote improved trial design in upcoming randomized clinical trials in childhood chronic kidney disease (CKD), insight in the within- and inter-patient variability of uremic toxins with its nutritional, treatment- and patient-related confounding ...
Evelien Snauwaert +11 more
doaj +1 more source
Liver Injury Repair and Regeneration: Molecular Mechanisms and Therapeutic Targets
This review outlines the spatiotemporal framework of liver injury repair and regeneration, orchestrated by molecular signaling, multicellular niche crosstalk, metabolic reprogramming, and interorgan communication. Post‑injury regenerative cascades (initiation, proliferation, termination) rely on crosstalk between hepatocytes, Kupffer cells, hepatic ...
Mingyue Pan +15 more
wiley +1 more source
Gastroschisis‐Like Defect in a Crossbred Bovine Calf: Anatomical, Clinical and Surgical Perspectives
A gastroschisis‐like defect was observed in a one‐day‐old, crossbred bovine calf with evisceration of the pyloric abomasum and small intestine, likely resulting from prenatal rupture of an omphalocele. The calf presented with lethargy, hypothermia and metabolic derangements, along with elevated renal biomarkers.
Mohammad Raguib Munif +1 more
wiley +1 more source
ABSTRACT Light chain monoclonal gammopathy of undetermined significance (LC‐MGUS) is defined by an abnormal serum free light chain ratio and elevated involved light chain in the absence of a detectable immunoglobulin heavy chain on immunofixation and of end‐organ damage attributable to a plasma cell disorder.
Sigurður Yngvi Kristinsson +2 more
wiley +1 more source
HIV‐associated nephropathy: A decade of clinical outcomes, global disparities and emerging promise
Abstract Objective To review the pathogenesis, epidemiology, clinical presentation, management and outcomes of HIV‐associated nephropathy (HIVAN), with emphasis on global disparities, genetic susceptibility (APOL1) and emerging therapeutic and technological advances.
Deepak V. Pathiyil +4 more
wiley +1 more source
ABSTRACT An illegal laboratory discovered in Reedley, California, in December 2022 was in a warehouse, operating without a license, handling about a thousand transgenic mice, chemicals, and possibly over 20 pathogens, including vials labeled Ebola, which were never tested but destroyed.
Atalay Goshu Muluneh +7 more
wiley +1 more source

