Future of Uremic Toxin Management [PDF]
ToxinsDuring the progression of chronic kidney disease (CKD), the retention of uremic toxins plays a key role in the development of uremic syndrome. Knowledge about the nature and biological impact of uremic toxins has grown exponentially over the past decades.
Raymond Vanholder +3 more
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A Systematic Review of Uremic Toxin Concentrations and Cardiovascular Risk Markers in Pediatric Chronic Kidney Disease [PDF]
ToxinsChronic kidney disease (CKD) can lead to cardiac dysfunction in a condition known as cardiorenal syndrome (CRS). It is postulated that the accumulation of uremic toxins in the bloodstream, as a consequence of declining kidney function, may contribute to ...
Heshini Dalpathadu +3 more
doaj +2 more sources
Assessment of Within- and Inter-Patient Variability of Uremic Toxin Concentrations in Children with CKD [PDF]
ToxinsTo promote improved trial design in upcoming randomized clinical trials in childhood chronic kidney disease (CKD), insight in the within- and inter-patient variability of uremic toxins with its nutritional, treatment- and patient-related confounding ...
Evelien Snauwaert +11 more
doaj +2 more sources
Comprehensive Bibliometric Analysis of Uremic Toxin Research [PDF]
ToxinsUremic toxins accumulate as kidney disease progresses, contributing to diverse systemic disorders. Despite numerous studies, no comprehensive mapping has been performed.
Marsuki Hardjo +4 more
doaj +2 more sources
From Physicochemical Classification to Multidimensional Insights: A Comprehensive Review of Uremic Toxin Research [PDF]
ToxinsChronic kidney disease (CKD) is a global health burden, with uremic toxins (UTs) playing a central role in its pathophysiology. In this review, we systematically examined the evolution of UT classification from the 2003 European Uremic Toxin Work Group ...
Mario Cozzolino +2 more
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Hemodiafiltration with endogenous reinfusion for uremic toxin removal in patients undergoing maintenance hemodialysis: a pilot study [PDF]
Renal FailureObjective To delineate the efficacy and safety profile of hemodiafiltration with endogenous reinfusion (HFR) for uremic toxin removal in patients undergoing maintenance hemodialysis (MHD).Methods Patients who have been on MHD for a period of at least 3 ...
Renhua Lu +8 more
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Comparison of uremic toxin removal between expanded hemodialysis and high volume online hemodiafiltrations in different modes [PDF]
Acta Biochimica PolonicaVarious high-efficiency hemodialysis techniques exist, including different online high- volume hemodiafiltration (HDF) modes and expanded hemodialysis (HDx) utilizing dialyzers with medium cut-off (MCO) membranes.
Jan Biedunkiewicz +10 more
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Uremic Toxins and Protein-Bound Therapeutics in AKI and CKD: Up-to-Date Evidence
Toxins, 2021 Uremic toxins are defined as harmful metabolites that accumulate in the human body of patients whose renal function declines, especially chronic kidney disease (CKD) patients. Growing evidence demonstrates the deteriorating effect of uremic toxins on CKD
Jia-Huang Chen, Chih-Kang Chiang
doaj +1 more source
Critical Care Explorations, 2021 OBJECTIVES:. Shiga toxin-producing Escherichia coli infection is associated with dysentery and the hemolytic uremic syndrome, marked by the triad of microangiopathic hemolytic anemia, acute kidney failure, and thrombocytopenia.
Charles G. Volk, MD +4 more
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Elimination of endogenous toxin, creatinine from blood plasma depends on albumin conformation: site specific uremic toxicity & impaired drug binding. [PDF]
PLoS ONE, 2011 Uremic syndrome results from malfunctioning of various organ systems due to the retention of uremic toxins which, under normal conditions, would be excreted into the urine and/or metabolized by the kidneys.
Ankita Varshney +4 more
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