Results 41 to 50 of about 25,775 (238)

New insights in uremic toxins [PDF]

Kidney International, 2003
The retention in the body of compounds, which normally are secreted into the urine results in a clinical picture, called the uremic syndrome. The retention compounds responsible for the uremic syndrome are called uremic toxins. Only a few of the uremic retention solutes fully conform to a true definition of uremic toxins.
Vanholder, Raymond, Glorieux, Griet, De Smet, Rita, Lameire, Norbert   +3 more
openaire   +2 more sources

Enterohemorrhagic Escherichia coli colonization of human colonic epithelium in vitro and ex vivo [PDF]

, 2015
Enterohemorrhagic E. coli (EHEC) are important foodborne pathogens causing gastroenteritis and more severe complications such as hemorrhagic colitis and hemolytic uremic syndrome.
B. A. McCormick, Richard Tighe, Stephanie Schüller, Steven B. Lewis, Vivienne Cook   +4 more
core   +1 more source

Genotyping and antimicrobial resistance patterns of Escherichia coli O157 originating from cattle farms [PDF]

, 2011
During a Escherichia coli O157 prevalence study on cattle farms, 324 E. coli O157 isolates were collected from 68 out of 180 cattle farms. All isolates harbored the eaeA gene and the enterohemolysin (ehxA) gene. The majority of the strains only contained
Boyen, Filip, Cobbaut, Katrijn, De Zutter, Lieven, Haesebrouck, Freddy, Houf, Kurt   +4 more
core   +1 more source

Nrf2 Activation in Chronic Kidney Disease: Promises and Pitfalls

Antioxidants, 2022
The nuclear factor erythroid 2-related factor 2 (Nrf2) protects the cell against oxidative damage. The Nrf2 system comprises a complex network that functions to ensure adequate responses to redox perturbations, but also metabolic demands and cellular ...
Ana Karina Aranda-Rivera, Alfredo Cruz-Gregorio, José Pedraza-Chaverri, Alexandra Scholze   +3 more
doaj   +1 more source

Targeting Uremic Toxins to Prevent Peripheral Vascular Complications in Chronic Kidney Disease

Toxins, 2020
Chronic kidney disease (CKD) exhibits progressive kidney dysfunction and leads to disturbed homeostasis, including accumulation of uremic toxins, activated renin-angiotensin system, and increased oxidative stress and proinflammatory cytokines.
Chia-Lin Wu, Der-Cherng Tarng
doaj   +1 more source

Mild Illness during Outbreak of Shiga Toxin−Producing Escherichia coli O157 Infections Associated with Agricultural Show, Australia

Emerging Infectious Diseases, 2017
During a large outbreak of Shiga toxin−producing Escherichia coli illness associated with an agricultural show in Australia, we used whole-genome sequencing to detect an IS1203v insertion in the Shiga toxin 2c subunit A gene of Shiga toxin−producing E ...
Bhakti R. Vasant, Russell J. Stafford, Amy V. Jennison, Sonya M. Bennett, Robert J. Bell, Christine J. Doyle, Jeannette R. Young, Susan A. Vlack, Paul Titmus, Debra El Saadi, Kari A.J. Jarvinen, Patricia Coward, Janine Barrett, Megan Staples, Rikki M.A. Graham, Helen V. Smith, Stephen B. Lambert   +16 more
doaj   +1 more source

Heparin-induced thrombocytopenia following Shiga-toxin-associated hemolytic uremic syndrome: a case report

Journal of Medical Case Reports, 2022
Background Up to 50% of cases of Shiga-toxin-producing Escherichia coli hemolytic uremic syndrome occur in adults, and the clinical presentation is variable.
Elia Rigamonti, Tecla Bonora, Mariangela Ventresca, Pietro Cippà   +3 more
doaj   +1 more source

Lipid Profile Is Negatively Associated with Uremic Toxins in Patients with Kidney Failure—A Tri-National Cohort

Toxins, 2022
Patients with kidney failure (KF) have a high incidence of cardiovascular (CV) disease, partly driven by insufficient clearance of uremic toxins. Recent investigations have questioned the accepted effects of adverse lipid profile and CV risk in uremic ...
Sam Hobson, Henriette de Loor, Karolina Kublickiene, Joachim Beige, Pieter Evenepoel, Peter Stenvinkel, Thomas Ebert   +6 more
doaj   +1 more source

Chronic Kidney Disease Increases Cerebral Microbleeds in Mouse and Man. [PDF]

, 2020
Brain microbleeds are increased in chronic kidney disease (CKD) and their presence increases risk of cognitive decline and stroke. We examined the interaction between CKD and brain microhemorrhages (the neuropathological substrate of microbleeds) in ...
Bangash, Maria, Cribbs, David H, Fisher, Mark, Floriolli, David, Lau, Wei Ling, Lertpanit, Long, Naqvi, Sameen, Nunes, Ane CF, Paganini-Hill, Annlia, Savoj, Javad, Shah, Krunal, Vasilevko, Vitaly, Vaziri, Nosratola D, Yao, Zhihui   +13 more
core  

Uremic toxins mediate kidney diseases: the role of aryl hydrocarbon receptor

Cellular & Molecular Biology Letters
Aryl hydrocarbon receptor (AhR) was originally identified as an environmental sensor that responds to pollutants. Subsequent research has revealed that AhR recognizes multiple exogenous and endogenous molecules, including uremic toxins retained in the ...
Hongyan Xie, Ninghao Yang, Chen Yu, Limin Lu   +3 more
doaj   +1 more source