Results 101 to 110 of about 5,112,493 (265)
Arthritis Research & Therapy, 2018 BackgroundIn addition to the kidney, the intestine is one of the most important organs involved in uric acid excretion. However, the mechanism of urate excretion in the intestine remains unclear.
Mo Chen +6 more
semanticscholar +1 more source
THE EFFECT OF DIODRAST ON THE NORMAL URIC ACID CLEARANCE 1 [PDF]
, 1944 Roy W. Bonsnes +2 more
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Renal Failure, 2018 Objectives: Whether uric acid levels were associated with the progression of chronic kidney disease (CKD) remained controversial. This meta-analysis was aimed to assess the effect of lowering serum uric acid therapy on the progression of CKD to clarify ...
Xuemei Liu +5 more
semanticscholar +1 more source
Correlation between serum levels of uric acid with bone turnover markers in postmenopausal women
Iranian South Medical Journal, 2015 Background: There is accumulation evidence regarding the protective role of higher serum uric acid in bone loss and osteoprotic fractures. This effect may arise from its antioxidant properties.
Fariba Karimi +8 more
doaj
Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review [PDF]
European Medical Journal Nephrology, 2016 In this review, the authors briefly examine the most recent evidence concerning the role of several proteins involved in tubular urate transport. They also analyse the influence of extracellular volume, electrolyte disorders, acid-base imbalance, and ...
Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review +4 more
doaj
Uric acid transporter inhibitors for gout
ADMET and DMPK, 2017 Gout is a common inflammatory arthritis that is caused by chronically-elevated serum uric acid (sUA) levels (hyperuricemia). In humans, sUA levels are predominantly controlled by a variety of transporters that mediate the elimination of uric acid through
Philip K. Tan, Jeffrey N. Miner
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Scientific Reports, 2018 Serum uric acid level is a risk factor for cardiovascular disease (CVD). However, whether it is an independent risk factor or not remains controversial. We analyzed the association between serum uric acid level and cardiovascular risk.
Chun-Chin Chang +7 more
semanticscholar +1 more source
High uric acid model in Caenorhabditis elegans
Food Science and Human Wellness, 2019 To establish experimental high uric acid model in C. elegans. Hypoxanthine, adenine, xanthine, and uric acid were used to treat C. elegans and then hyperuricemic C. elegans was evaluated by allopurinol. Hyperuricemic C. elegans were obtained after normal
Zhenjing Li +6 more
doaj
The systems biology of uric acid transporters: the role of remote sensing and signaling
Current opinion in nephrology and hypertension, 2018 Purpose of review Uric acid homeostasis in the body is mediated by a number of SLC and ABC transporters in the kidney and intestine, including several multispecific ‘drug’ transporters (e.g., OAT1, OAT3, and ABCG2).
S. Nigam, V. Bhatnagar
semanticscholar +1 more source
The Employment of Uric Acid Synthetic Medium for the Differentiation of B. Coli and B. Aerogenes [PDF]
, 1918 S. A. Koser
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