Results 131 to 140 of about 5,236,042 (380)

Engineering DNA Origami Captors for TGFβ1 Sequestration to Enhance Tumor Immune Modulation and Therapy

open access: yesAdvanced Science, EarlyView.
Programmable DNA framework captors effectively deplete circulatingtransforming growth factor‐β1 (TGFβ1) through fast systemic clearance and reshape the tumor immune microenvironment, alleviating immunosuppression to inhibit tumor progression. Abstract Efficient modulation of pivotal immune‐regulatory molecules to leverage the tumor microenvironment ...
Xiao Chen   +7 more
wiley   +1 more source

Uric Acid and Cognitive Function in Older Individuals

open access: yesNutrients, 2018
Hyperuricemia has been recognized as an independent cardiovascular risk factor in epidemiological studies. However, uric acid can also exert beneficial functions due to its antioxidant properties, which may be particularly relevant in the context of ...
C. Tana   +4 more
semanticscholar   +1 more source

Concordance of gout management with European League against Rheumatism recommendations in hospital practice [PDF]

open access: yes, 2010
Aim: To assess the concordance of gout management with the European League Against Rheumatism (EULAR) gout recommendations in hospital practice. Methods: This was a retrospective review of case notes of patients presenting to rheumatology outpatients ...
Attard Cortis, Petramay   +3 more
core  

Sweat Wearable Sensor Based on Confined Pt Nanoparticles in 2D Conductive Metal–Organic Frameworks for Continuous Glucose Monitoring

open access: yesAdvanced Science, EarlyView.
An integrated wearable system is developed for nonenzymatic sweat glucose monitoring at the point of care. The system couples a microfluidic patch based on Pt nanoparticles confined in phthalocyanine‐based conductive MOFs with a flexible wireless circuit.
Wei Huang   +4 more
wiley   +1 more source

Soluble uric acid increases PDZK1 and ABCG2 expression in human intestinal cell lines via the TLR4-NLRP3 inflammasome and PI3K/Akt signaling pathway

open access: yesArthritis Research & Therapy, 2018
BackgroundIn addition to the kidney, the intestine is one of the most important organs involved in uric acid excretion. However, the mechanism of urate excretion in the intestine remains unclear.
Mo Chen   +6 more
semanticscholar   +1 more source

Effects of speed, heart rate, lactate and uric acid on the performance of Arabian horses during a 120-Km endurance race [PDF]

open access: yes, 2012
Speed, heart rate, lactate and uric acid alterations led to reduced performance and hamper the health status of endurance horses. The aim of this study was to investigate on the effects of speed, heart rate, lactate and uric acid on the performance of ...
Abdullah, Rasedee   +3 more
core  

Time‐Decoupled Electrolysis via a Rechargeable Metal‐Urea Battery for Waste Urea Treatment and Hydrogen Production

open access: yesAdvanced Science, EarlyView.
A rechargeable metal‐urea battery is reported with a time‐decoupled splitting mechanism, separating urea oxidation during charging and hydrogen evolution during discharging, to eliminate kinetic mismatches and boost efficiency. The development of the temporally decoupled rechargeable metal‐urea battery for hydrogen production not only addresses urea ...
Dong Lv   +4 more
wiley   +1 more source

Molecular Engineering of Ionic Metal‐Organic Frameworks via Ligand Conjugation Modulation for Tailored Phosphorescence and Multilevel Encryption

open access: yesAdvanced Science, EarlyView.
This work exhibits a molecular engineering approach for efficient equilibrium phosphorescence through guest ion‐mediated ligand conjugation to modulate ionic Metal‐Organic Frameworks excited state dynamics. The designed IMOF‐DMF realizes temperature‐responsive room‐temperature phosphorescence and multi‐state lifetime encoding for anti‐counterfeiting ...
Qi Wu   +3 more
wiley   +1 more source

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